Sentinel Lymph Node Biopsy in Breast Cancer: Current Status and Recent Progress

  • Amina Maimaitiaili
  • Zhenyu Liu
  • Di Wu
  • Zhimin FanEmail author
Review Article


Sentinel lymph node biopsy (SLNB) is a standard procedure used to evaluate the status of axillary lymph nodes (ALNs) that are clinically tumor-free in patients with early-stage breast cancer. Recent research on SLNB has led to continual improvements in the scope of application, accuracy in information provided, and relevance of the results for subsequent treatment. This review is based on selective searches of the Springer Publishing Company and PubMed databases for articles about progress and developments of SLNB in patients with breast cancer. The main purposes are to summarize the current status and established indications for SLNB, identify specific topics that are still under debate, and suggest specific areas where further studies are most needed.


Sentinel lymph node biopsy Axillary lymph node dissection Breast cancer Neoadjuvant chemotherapy Isolated tumor cells Micrometastases 



We are grateful to our colleagues and their families for supporting the work.

Author Contribution

All authors have read and approved the submission of the manuscript.

Compliance with Ethical Standards

Conflict of interest

The manuscript has not been published and is not being considered for publication elsewhere, in whole or in part, in any language, except as an abstract. The authors declare that they have no competing interests.


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Copyright information

© Association of Surgeons of India 2019

Authors and Affiliations

  • Amina Maimaitiaili
    • 1
  • Zhenyu Liu
    • 1
  • Di Wu
    • 1
  • Zhimin Fan
    • 1
    Email author
  1. 1.Department of Breast SurgeryFirst Hospital of Jilin UniversityChangchunChina

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