Gallbladder Metastasis from Renal Cell Carcinoma
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We experienced a rare case of gallbladder metastasis from renal cell carcinoma. A 68-year-old man was admitted for further evaluation of a gallbladder tumor, which had been identified on follow-up computed tomography after partial nephrectomy for renal cell carcinoma. Enhanced computed tomography and magnetic resonance imaging showed an enhancing polypoid mass in the gallbladder lumen. Endoscopic ultrasonography demonstrated a homogenous hypo-echoic polypoid lesion, and the outer hyper-echoic layer of the adjacent wall was intact. Blood flow signals in the wall side of the mass were observed on color Doppler endoscopic ultrasonography images. Laparoscopic cholecystectomy was performed and he was uneventfully discharged. Macroscopic examination of the specimen revealed a 12 × 7 × 5 mm pedunculated tumor attached by a thin pedicle to the fundus of the gallbladder. Histology confirmed a metastasis of the renal cell carcinoma that had infiltrated the shallow subserosa but had mainly grown into cavity of the gallbladder. These imaging findings are considered characteristic and may assist preoperative diagnosis in patients with a history of renal cell carcinoma.
KeywordsGallbladder metastasis Renal cell carcinoma Laparoscopic cholecystectomy Clear cell renal cell carcinoma
Authors would like to thank Hiroshi Kurumaya, M.D.,Ph.D., for providing histological images.
Compliance with Ethical Standards
This study has been approved by the research ethics committee of Ishikawa Prefectural Central Hospital.
The identity of the patients has been protected.
Written informed consent was obtained from the patient for publication of this case report and accompanying images.
Conflict of Interest
The authors declare that they have no conflict of interest.
- 1.Nojima H, Cho A, Yamamoto H, Nagata M, Takiguchi N, Kainuma O, Souda H, Gunji H, Miyazaki A, Ikeda A, Matsumoto I, Asano T, Ryu M, Nihei N, Maruoka M (2008) Renal cell carcinoma with unusual metastasis to the gallbladder. J Hepato-Biliary-Pancreat Surg 15(2):209–212. https://doi.org/10.1007/s00534-007-1226-5
- 4.Kurokami T, Kikuyama M, Morita T, Shigetomo M, Kimura Y, Maruno T, Kayahara T, Matsumura K, Suzuki M (2012) A case of metastatic gallbladder tumor of renal cell cancer with a unique feature followed by ultrasonography. JJBA 26:699–704Google Scholar
- 5.Ishizawa T, Okuda J, Kawanishi T, Kitagawa T, Yakumaru K, Sekikawa T (2006) Metastatic renal cell carcinoma of the gallbladder. Asian J Surg 29(3):145–148. https://doi.org/10.1016/S1015-9584(09)60074-9