Indian Journal of Surgery

, Volume 79, Issue 6, pp 555–562 | Cite as

Predictive Factors for Small Intestinal and Colonic Anastomotic Leak: a Multivariate Analysis

  • Ahmad Sakr
  • Sameh Hany Emile
  • Emad Abdallah
  • Waleed Thabet
  • Wael Khafagy
Original Article


Anastomotic leak (AL) is a serious complication of intestinal surgery with various predisposing factors. This study aims to assess several risk factors associated with AL after small intestinal and colonic anastomoses through a multivariate analysis. Two hundred twenty-four patients (126 males) with intestinal anastomosis of a median age of 44 years were reviewed. Independent factors associated with AL were male gender (OR = 2.59, P = 0.02), chronic liver disease (CLD) (OR = 8.03, P < 0.0001), more than one associated comorbidity (OR = 5.34, P = 0.017), anastomosis conducted as emergency (OR = 2.73, P = 0.012), colonic anastomosis (OR = 2.51, P = 0.017), preoperative leukocytosis (OR = 2.57, P = 0.015), and intraoperative blood transfusion (OR = 2.25, P = 0.037). Predicative factors significantly associated with AL were male gender, CLD, multiple comorbidities, emergent anastomoses, colonic anastomoses, preoperative leukocytosis, and intraoperative blood transfusion.


Anastomotic leak Risk factors Multivariate analysis Colonic anastomosis 


Compliance with Ethical Standards

Ethical approval was obtained from the institutional review board of Mansoura Faculty of Medicine.

Conflict of Interest

The authors declare that they have no conflict of interest.


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Copyright information

© Association of Surgeons of India 2016

Authors and Affiliations

  • Ahmad Sakr
    • 1
  • Sameh Hany Emile
    • 1
  • Emad Abdallah
    • 1
  • Waleed Thabet
    • 1
  • Wael Khafagy
    • 1
  1. 1.Department General surgery, Faculty of MedicineMansoura University HospitalsMansoura cityEgypt

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