Indian Journal of Surgery

, Volume 77, Supplement 1, pp 16–18 | Cite as

Primary Appendiceal Adenocarcinoma Masquerading as Primary Bladder Tumor: a Case Report and Review of Literatures

  • Rui Qu
  • Yong Jiang
  • Shihe Chen
  • Qiang DongEmail author
Case Report


Adenocarcinoma of the appendix invading the urinary bladder is very rare. We describe such a case in a 42-year-old man and review the relevant literatures. In the present case, although ultrasonography and computed tomography scan revealed a mass in the bladder or in the pelvic and biopsies by cystoscopy showed an adenocarcinoma suspicious for primary of the bladder, its real origin was hard to distinguish. An open exploratory surgery was performed with subsequent resection of appendix and partial bladder. Postoperative histopathological examinations revealed the appendiceal adenocarcinoma infiltrating the bladder wall. The patient refused the right hemicolectomy and received 3 cycles of adjuvant radiotherapy. However, tumor recurrence was found in the bladder 6 months after surgery, and radical cystectomy was eventually performed.


Adenocarcinoma Appendiceal neoplasms Urinary bladder neoplasms 


Conflict of Interest

We declare that none of the authors have any financial and personal relationships with other people or organizations that can inappropriately influence the quality of the work presented in this manuscript.


  1. 1.
    Murphy EM, Farquharson SM, Moran BJ (2006) Management of an unexpected appendiceal neoplasm. Br J Surg 93:83–92CrossRefGoogle Scholar
  2. 2.
    Vidarsdottir H, Moller PH, Benediktsdottir KR, Geirsson G (2010) Adenocarcinoma of the appendix with a fistula to the urinary bladder. Scand J Urol Nephrol 44:354–356CrossRefPubMedGoogle Scholar
  3. 3.
    Mistry R, Ananthakrishnan K, Hamid BN, Powell C, Foster GE (2006) Appendiceal carcinoma masquerading as recurrent urinary tract infections: case report and review of literature. Urology 68(428):e1–e3PubMedGoogle Scholar
  4. 4.
    Arisawa C, Takeuchi S, Wakui M (2001) Appendiceal carcinoma invading the urinary bladder. Int J Urol 8:196–198CrossRefPubMedGoogle Scholar
  5. 5.
    Zhong M, Gersbach E, Rohan SM, Yang XJ (2013) Primary adenocarcinoma of the urinary bladder: differential diagnosis and clinical relevance. Arch Pathol Lab Med 137:371–381CrossRefPubMedGoogle Scholar
  6. 6.
    Chu PG, Chung L, Weiss LM, Lau SK (2011) Determining the site of origin of mucinous adenocarcinoma: an immunohistochemical study of 175 cases. Am J Surg Pathol 35:1830–1836CrossRefPubMedGoogle Scholar
  7. 7.
    Gustafsson B, Siddique L, Chan A, Dong M, Drozdov I, Kidd M, Modlin IM (2008) Uncommon cancers of the small intestine, appendix and colon: an analysis of SEER 1973–2004, and current diagnosis and therapy. Int J Oncol 33:1121–1131PubMedGoogle Scholar
  8. 8.
    Nitecki SS, Wolff BG, Schlinkert R, Sarr MG (1994) The natural history of surgically treated primary adenocarcinoma of the appendix. Ann Surg 219:51–57CrossRefPubMedCentralPubMedGoogle Scholar

Copyright information

© Association of Surgeons of India 2014

Authors and Affiliations

  1. 1.Department of Urology, West China HospitalSichuan UniversityChengduPeople’s Republic of China
  2. 2.Department of Pathology, West China HospitalSichuan UniversityChengduPeople’s Republic of China

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