Indian Journal of Surgery

, Volume 71, Issue 2, pp 73–77 | Cite as

The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats

Original Article



Peritoneal adhesions are fibrous bands of tissues formed between organs that are normally separated and/or between organs and the internal body wall after peritoneal injury. The aim of the study was to investigate the effect of intra-peritoneal administration of Kombucha on intra-peritoneal adhesions.

Materials and methods

Eighty Wistar rats were subjected to standardized lesion by scraping model and were randomly divided into two groups. Group I received no treatment, and Group II received 15 ml of Kombucha solution intra-peritoneally. On the post-operative 14th day adhesion intensity score, inflammatory cell reaction and number of adhesion bands were determined.


In the control group, there were no rats with grade 0 and I adhesions. In the group II, there were 26 rats (78.8%) with grade 0–2 adhesions. Adhesion intensity was significantly less in group II (P<0.0001). Number of adhesion bands was significantly less in group II (P<0.001).


It was concluded that intra-peritoneal administration of Kombucha might be useful for preventing peritoneal adhesions.


Peritoneal adhesions Kombucha Prevention 


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Copyright information

© Association of Surgeons of India 2009

Authors and Affiliations

  • Hemmat Maghsoudi
    • 1
  • Hussein Benagozar Mohammadi
    • 1
  1. 1.Department of Surgery, Faculty of MedicineUniversity of Medical Sciences of TabrizTabrizIran

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