The effect of cetylpyridinium chloride on halitosis and periodontal disease-related parameters in dogs

  • Se Eun Kim
  • Kyung Mi Shim
  • Kyeong Hoon Yoo
  • Jong-Choon Kim
  • Sung-Ho Kim
  • Chun-Sik Bae
  • Doman Kim
  • Don Hee Park
  • Ji-Won Ryu
  • Seong Soo Kang
Article
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Abstract

Periodontal disease is an oral disease common in middle-aged dogs and cats, with halitosis being the most common sign. There are many commercial products containing chlorhexidine, cetylpyridinium chloride (CPC), zinc salts and essential oils for controlling halitosis and periodontal disease. CPC is a quaternary ammonium compound and has a broad spectrum antimicrobial activity. In this study, oral spray (OS) and gel (OG) containing CPC was applied to the dogs’ teeth twice daily for 3 weeks, and their effect in controlling periodontal disease and halitosis was examined. In the 3-week study, OS and OG were significantly effective in controlling plaque, calculus, and halitosis. Therefore, the OS and OG containing CPC were effective in controlling periodontal disease and halitosis in dogs.

Keywords

cetylpyridinium chloride halitosis periodontal disease dog 
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Copyright information

© The Korean Society for Biotechnology 2008

Authors and Affiliations

  • Se Eun Kim
    • 1
  • Kyung Mi Shim
    • 1
  • Kyeong Hoon Yoo
    • 1
  • Jong-Choon Kim
    • 1
  • Sung-Ho Kim
    • 1
  • Chun-Sik Bae
    • 1
  • Doman Kim
    • 2
  • Don Hee Park
    • 2
  • Ji-Won Ryu
    • 3
  • Seong Soo Kang
    • 1
  1. 1.College of Veterinary MedicineChonnam National UniversityGwangjuKorea
  2. 2.School of Biological Sciences and TechnologyChonnam National UniversityGwangjuKorea
  3. 3.Department of Oral medicine, Dental CollegeChosun UniversityGwangjuKorea

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