Pancreatic neuroendocrine tumours – new therapeutic concepts
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Neuroendocrine tumours (NETs) are rare tumours with their clinical behaviour depending on the location of the primary and grade of differentiation. Recently, a number of randomised studies have been published focussing on pancreatic NETs which have demonstrated the efficacy of new therapeutic approaches including thyrosin-kinase inhibition and targetting the mTOR pathway. The objective of this review is to briefly sum up systemic treatment options in well differentiated pancreatic neuroendocrine tumours which are currently available.