Difficult Causality Relationship between Colorectal Cancer and Schistosomiasis

  • Tchin DarreEmail author
  • Toukilnan Djiwa
  • Sassil Dare
  • Fousseni Alassani
  • Gado Napo-Koura
Letter to the Editor


The purpose of the study was to determine the nature of the association between colorectal cancer and schistosomiasis infection. This was a retrospective and descriptive study of colorectal cancers and to identify cases associated with schistosomiasis. A total of 814 cases of rectal colorectal cancer were collected and 3 cases were associated with schistosomiasis. These are 2 cases of Liberkunian adenocarcinoma and one case of malt lymphoma. The patients were all farmers and from rural areas. A co-infection with HIV was found in his 3 patients. Our data show an extreme rarity of the association colorectal cancer and schistosomiasis; it seems difficult to conceive of a causal relationship.


Colorectal cancer Schistosomiasis HIV Carcinoma Lymphoma 



Acquired Immune Deficiency Syndrome


Human Immonodeficiency Virus


World Health Organization


Author’s Information

TD, TDj and GNK are medical doctors in pathology; SD and FA are medical doctors in visceral surgery.

Authors’ Contributions

TD: is responsible for the conception of the study, participated in the study design, performed the laboratory analysis and interpretation, and wrote the paper. TDj, SD, and FA were involved in the clinical and therapeutic management of the patient; they have reviewed the paper. GNK was responsible for the overall scientific management of the study and the preparation of the final paper. All the authors have read and approved the final paper to be submitted for publication.

Compliance with Ethical Standards

Ethics Approval and Consent to Participate

This study received approval from the head of the laboratory department to be conducted (Ref N° 08/2017/LAP/CHUSO).

Consent to Publish

Written informed consent for publication of their clinical details and clinical images was obtained from the patient. A copy of the consent form is available for review by the Editor of this journal.

Availability of Data and Materials

All data generated or analysed during this study are included in this published article.

Conflict of Interests

The authors declare that they have no competing interests.


  1. 1.
    Plummer M, de Martel C, Vignat J, Ferlay J, Bray F, Franceschi S (2016) Global burden of cancers attributable to infections in 2012: a synthetic analysis. Lancet Glob Health 4(9):e609–e616CrossRefGoogle Scholar
  2. 2.
    Lapoile E, Bellaiche G, Boucard M et al (2008) Cancer du rectum associé à une infection à Schistosoma hematobium. Gastroenterol Clin Biol 30(10):1225–1226CrossRefGoogle Scholar
  3. 3.
    Darré T, Kpatcha K, Tchaou M et al (2015) Histological aspect of urinary schistosomiasis in Togo: results of a cohort of 192 cases. Bull Soc Pathol Exot 108(2):124–125CrossRefGoogle Scholar
  4. 4.
    Ferguson AR (1911) Associated bilharziosis and primary malignant disease of the urinary bladder with observations on a series of forty cases. J Pathol Bacteriol 16(1):76–94CrossRefGoogle Scholar
  5. 5.
    Gaye AM, Doh K, Thiam I, Bentefouet L, Woto-Gaye G (2016) Schistosomiasis and cancer: a fortuitous association or relationships cause and effect. Bull Cancer 103(9):806–807CrossRefGoogle Scholar

Copyright information

© Arányi Lajos Foundation 2019

Authors and Affiliations

  • Tchin Darre
    • 1
    • 2
    Email author
  • Toukilnan Djiwa
    • 1
  • Sassil Dare
    • 3
  • Fousseni Alassani
    • 3
  • Gado Napo-Koura
    • 1
  1. 1.Department of PathologyUniversity Teaching Hospital of LomeLoméTogo
  2. 2.University of LomeLoméTogo
  3. 3.Department of Visceral SurgeryUniversity Teaching Hospital of LomeLoméTogo

Personalised recommendations