Pathology & Oncology Research

, Volume 16, Issue 2, pp 143–148

Panitumumab: An Arrow on Target

Article

Abstract

Several options are available today in the treatment of advanced colorectal cancer: traditional chemotherapeutic regimens, targeted therapies, and their combinations. Panitumumab is a new, fully human anti-EGFR monoclonal antibody, what is well-tolerated, effective as a single agent in chemotherapy refractory patients and in different combinations. The clinical response is restricted to tumors with wild-type RAS, therefore the RAS status should be checked before treatment.

Keywords

Panitumumab Colorectal cancer Anti-EGFR therapy 

Copyright information

© Arányi Lajos Foundation 2010

Authors and Affiliations

  1. 1.Ist Department of Pathology and Experimental Cancer ResearchSemmelweis UniversityBudapestHungary

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