Virologica Sinica

, Volume 33, Issue 3, pp 282–286 | Cite as

Emergence of Eurasian Avian-Like Swine Influenza A (H1N1) Virus from an Adult Case in Fujian Province, China

  • Jian-Feng Xie
  • Yan-Hua Zhang
  • Lin Zhao
  • Wen-Qiong Xiu
  • Hong-Bin Chen
  • Qi Lin
  • Yu-Wei Weng
  • Kui-Cheng ZhengEmail author

Dear Editor,

As we known, pigs play a vital role as genetic mixing vessels for human and avian influenza viruses as their tracheal epitheliums possess both sialic acid α-2,6-Gal and α-2,3-Gal receptors (Ma et al.2008), and swine influenza viruses occasionally infect humans (Shinde et al.2009). The Eurasian avian-like swine influenza A (H1N1) virus (EAS-H1N1) spread into China around 2007, when the first isolate (A/swine/Fujian/204/2007) from pigs in Fujian was reported via swine influenza surveillance program (Liu et al.2009). Much later, three cases of EAS-H1N1 infection in human were reported in China and they were all children under the age of three (Yang et al.2012; Wang et al.2013; Zhu et al.2016), whereas the forth case was an adult, who was confirmed in October, 2016, in Fujian province.

The patient was a 46-year-old man with fever of 39 °C and started coughing on October 19, 2016. In the day after onset, he was treated in a prefectural hospital on account of hemoptysis and...



We thank Fuzhou Center for Disease Control and Prevention and Fuzhou Pulmonary Hospital for providing the sample. We acknowledge the contributions of authors and laboratories for sharing the influenza virus sequences in GISAID’s EpiFlu Database. This study was supported by the fund of Natural Science Foundation of Fujian Province (2015J01294), the Youth Backbone Talents Cultivation Program of Health System in Fujian Province (2015-ZQN-ZD-10) and the National Science and Technology Major Project (2017ZX10103008).

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Animal and Human Rights Statement

The study was approved by the ethics committees of Fujian Provincial Center for Disease Control and Prevention. All participants provided written informed consent. Written consents were obtained from all participants involved in the study.


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Copyright information

© Wuhan Institute of Virology, CAS and Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Fujian Provincial Center for Disease Control and PreventionFujian Provincial Key Laboratory of Zoonoses ResearchFuzhouChina
  2. 2.School of Public HealthFujian Medical UniversityFuzhouChina

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