A novel mosquito-borne reassortant orbivirus isolated from Xishuangbanna, China
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The genus Orbivirus, within the family Reoviridae, includes 22 virus species (King et al., 2011). They are distributed globally, but are particularly prevalent in Europe, Asia, and Africa. In addition, they can be transmitted by ticks or other hematophagous insect vectors, including Culicoides, mosquitoes, and sandflies (Belaganahalli et al., 2015).
Orbiviruses contain double-stranded RNA as their genetic material, which includes 10 segments (S1–S10) of various lengths. Owing to this segmented structure, genetic reassortment occurs frequently among orbiviruses. Reassortment occurs when different segmented viruses of the same vector type infect a single host cell, and genomic segments of the “parental” viruses are exchanged and repackaged during progeny formation (Simon-loriere and Holmes, 2011). Reassortment can result in novel viral genotypes and subsequent phenotypes, which can alter the mechanism of immune escape, the potential range of hosts or vectors, and the...
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