An In-line, High Sensitivity, Non-contact Sensor for the Detection of Initiation of Sticking
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In this paper, the development and testing of a laser sensor to detect initiation of sticking are discussed.
The basic working principle of the device involves a laser source aimed at the punch tip, and a photosensor measuring the intensity of the reflected beam.
The initial results show that the laser sensor can detect the accumulation of material on a flat punch tip and has the potential to be used as a real-time monitoring device during tablet manufacturing operations.
This work demonstrated that the laser sensor can characterize initiation of sticking with high sensitivity without the need to interrupt the compaction process as typically done with other sticking characterization techniques.
KeywordsSticking Tablet defects Laser sensor
The authors would like to thank GlaxoSmithKline for their financial support and access to instrumentation.
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