SAR characterization inside intracranial tumors for case–control epidemiological studies on cellular phones and RF exposure

  • Nadège Varsier
  • Kanako Wake
  • Masao Taki
  • Soichi Watanabe
  • Toru Takebayashi
  • Naohito Yamaguchi
  • Yuriko Kikuchi
Original Paper


Epidemiological studies investigating whether mobile phone use is related to cancer risk have been conducted in many countries. The purpose of the work reported here was to introduce the dose metric in the exposure assessment, taking into account the spatial distribution of exposure. Distributions of specific absorption rate (SAR) inside 275 cases of brain tumors (participants in the Japanese epidemiological study) were estimated. Phones had been classified into four categories based on SAR distributions and technical specifications. Results were found to be highly dependent on phone categories. Contralateral tumors were generally categorized as non-exposed tumors (max SAR <2.5% of max SAR in the brain) and, for any phone category, the maximum SAR in 75% of the ipsilateral tumors was less than 15% of the maximum SAR in the brain. Three new exposure indices combining the duration and strength of exposure were created to be used in the Japanese epidemiological study on mobile phone use and the risk of gliomas and meningiomas.


SAR characterization Mobile phones Epidemiological study Brain tumors RF exposure Cancer risk 



This work was supported in part by the Committee to Promote Research on the Possible Biological Effects of Electromagnetic Fields from the Japanese Ministry of Internal Affairs and Communications. We would like to thank Dr. Elisabeth Cardis (IARC) for her helpful comments and Dr. Joe Wiart (France Telecom R&D) for his valuable advice.


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Copyright information

© GET and Springer Verlag France 2008

Authors and Affiliations

  • Nadège Varsier
    • 1
    • 2
  • Kanako Wake
    • 2
  • Masao Taki
    • 1
  • Soichi Watanabe
    • 2
  • Toru Takebayashi
    • 3
  • Naohito Yamaguchi
    • 4
  • Yuriko Kikuchi
    • 3
  1. 1.Department of Electrical EngineeringTokyo Metropolitan UniversityTokyoJapan
  2. 2.National Institute of Information and Communications TechnologyTokyoJapan
  3. 3.Department of Preventive Medicine and Public HealthKeio University School of MedicineTokyoJapan
  4. 4.Department of Hygiene and Public HealthTokyo Women’s Medical UniversityTokyoJapan

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