Folia Microbiologica

, Volume 54, Issue 3, pp 213–216 | Cite as

Biolarvicidal activity of extracellular metabolites of the keratinophilic fungus Trichophyton mentagrophytes against arvae of Aedes aegypti — a major vector for Chikungunya and dengue

  • A. G. Murugesan
  • C. Sathesh Prabu
  • C. Selvakumar
Article

Abstract

The larvicidal activity of extracellular metabolites of keratinophilic fungus Trichophyton mentagrophytes against Aedes aegypti larvae was determined. T. mentagrophytes was isolated from soil by the feather baiting technique. Culture filtrates (10–100 μL/mL) were found to be entomotoxic to 3rd instars larvae of A. aegypti (L3), LC50 and LC90 being 110 ± 11.5 and 200 ± 20.7 μL/mL, respectively, after 2 d. Extracellular metabolites are proteinaceous in nature and more specific to chitin of mosquito larvae. They degraded cock feather causing an average of 20.0 ± 2.6 % loss in feather mass. Culture filtrate at 100 μL/mL produced 90 % mortality against L3 after 3 d; mortality was increased in dose- and time-dependent manner. These extracellular metabolites of T. mentagrophytes could be regarded as alternatives to synthetic insecticides.

Abbreviations

SDA

Sabouraud dextrose agar

L3

3rd instars larvae (of A. aegypti)

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Copyright information

© Institute of Microbiology, v.v.i, Academy of Sciences of the Czech Republic 2009

Authors and Affiliations

  • A. G. Murugesan
    • 1
  • C. Sathesh Prabu
    • 1
  • C. Selvakumar
    • 1
  1. 1.Sri Paramakalyani Centre for Environmental SciencesManonmaniam Sundaranar UniversityAlwarkurichiIndia

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