Applications of nanomaterials in modern medicine
- 381 Downloads
Nanomaterials represent a class of materials based on nanoscale structures. Nanomaterials are currently used in a wide variety of applications, including, optoelectronics, energy conversion, biology health care and medicine. Among different types of nanomaterials, gold nanoparticles have received considerable attention in disease diagnosis and therapy due to their optical and chemical properties (Liz-Marzan in Mater Today 7:26–31, 2004). This paper reports the main optical and photo-thermal properties of gold nanoparticles. Particularly, we show that gold nanorods embedded in cholesteric liquid crystals demonstrate to control the “selective reflection” of a light beam. Investigation of the optical properties of the obtained material reveals an original and efficient tool to detect temperature variations at the nanoscale useful for photo-thermal based therapies applications. Finally, the concept of ‘nanoparticle-protein corona interaction can be exploited for application ranging from regenerative medicine to theranostics.
KeywordsNanomaterials Plasmonics Photo-thermal therapy Nanomedicine
The research is supported by the Air Force Office of Scientific Research (AFOSR), Air Force Research Laboratory (AFRL), U.S. Air Force, under grant FA9550-14-1-0050 (P.I. L. De Sio, EOARD 2014/2015) and the Materials and Manufacturing Directorate, AFRL; by 2011 - prot. 2010C4R8M8 and 2012 prot. 2012T9XHH7 PRIN Projects. Fundings have been generously provided to GC by the “Futuro in Ricerca 2008” program funded by the Italian Minister for University and Research (grant no. RBFR08TLPO) and by the Istituto Italiano di Tecnologia, Center for Life Nano Science@Sapienza.
- Cattaneo AG, Gornati R, Bernardini G, Sabbioni E, Manzo L, Gioacchino MD (2014) Nanomedicine for the brain and the eye: disease management in poorly accessible compartments of the body. In: Sahu SC, Casciano DA (eds) Handbook of nanotoxicology, nanomedicine and stem cell use in toxicology. Wiley, New York, pp 223–248CrossRefGoogle Scholar
- Jhal RH, Jhal PK, Chaudhury K, Rana SV, Guha SK (2014) An emerging interface between life science and nanotechnology: present status and prospects of reproductive healthcare aided by nano-biotechnology. Nano Rev 5:22762–22780Google Scholar
- Yang Z, Chen M, Yang M, Chen J, Fang W, Xu P (2014) Evaluating the potential of cubosomal nanoparticles for oral delivery of amphotericin B in treating fungal infection. Int J Nanomed 9:327–336Google Scholar