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Psychological Injury and Law

, Volume 3, Issue 1, pp 50–62 | Cite as

Functional Neuroimaging of Symptom Validity Testing in Traumatic Brain Injury

  • Trevor ChuangKuo Wu
  • Mark D. AllenEmail author
  • Naomi J. Goodrich-Hunsaker
  • Ramona O. Hopkins
  • Erin D. Bigler
Article

Abstract

The Word Memory Test (WMT) is a commonly used symptom validity test (SVT) that assesses recognition verbal memory. The task has been adapted for use within a functional magnetic resonance imaging (fMRI) paradigm so the neural correlates of WMT activation patterns can be studied. In the current investigation, performance on the delayed recognition subtest of the WMT was examined in two patients who sustained severe TBI and compared to ten healthy controls. The patients underwent comprehensive neuropsychological evaluations and structural MRI. All participants completed two versions of the WMT: full-effort and simulated poor effort conditions. Despite extensive structural brain damage, the fMRI activation patterns during full-effort WMT performance were somewhat similar in the two TBI patients and likewise, somewhat similar to controls. The fMRI activation pattern in both patients demonstrated intact activation of the basic neural structures necessary to perform the WMT. Dissimilar patterns of activation were obtained during the simulated poor effort condition of WMT performance suggesting that fMRI techniques may be sensitive in demonstrating non-credible cognitive performance. The results of our study represent the first fMRI investigation of normal and simulated poor effort SVT performance in individuals with documented brain damage. The implications of fMRI techniques in SVT research and their clinical application are discussed.

Keywords

Functional magnetic resonance imaging (fMRI) Traumatic brain injury (TBI) Word memory test (WMT) Symptom validity test (SVT) 

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Copyright information

© Springer Science + Business Media, LLC. 2010

Authors and Affiliations

  • Trevor ChuangKuo Wu
    • 1
  • Mark D. Allen
    • 1
    • 2
    • 7
    Email author
  • Naomi J. Goodrich-Hunsaker
    • 2
    • 3
  • Ramona O. Hopkins
    • 1
    • 2
    • 4
    • 5
  • Erin D. Bigler
    • 1
    • 2
    • 5
    • 6
  1. 1.Department of PsychologyBrigham Young UniversityProvoUSA
  2. 2.Neuroscience CenterBrigham Young UniversityProvoUSA
  3. 3.NeuroTherapeutics Research Institute, Department of PsychiatryUniversity of California, Davis Medical CenterSacramentoUSA
  4. 4.Department of Medicine, Pulmonary and Critical Care DivisionIntermountain Medical CenterMurrayUSA
  5. 5.The Brain Institute of UtahUniversity of UtahSalt LakeUSA
  6. 6.Department of PsychiatryUniversity of UtahSalt LakeUSA
  7. 7.Department of Psychology and Neuroscience Center, 1001 SWKTBrigham Young UniversityProvoUSA

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