Journal of Mechanical Science and Technology

, Volume 32, Issue 12, pp 5737–5747 | Cite as

Current engineering and clinical aspects of needle-free injectors: A review

  • Abdul Mohizin
  • Jung Kyung Kim


Needle-free injectors can be used to achieve non-invasive drug delivery by impregnating biological barriers. They are considered as the future of drug delivery and therapeutic applications. The history of needle-free injectors dates back to the 1940s and these devices have been constantly evolving since then. Their operating principles and applications have been improved over the years. Herein, we review the current engineering mechanisms and clinical aspects of needle-free microjet injectors. The present study focuses on using engineering approaches to deal with various factors that affect the penetration and dispersion characteristics of the microjet.


Fluid dispersion Microjet Needle-free injection Penetration Skin Transdermal drug delivery 


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Copyright information

© The Korean Society of Mechanical Engineers and Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Mechanical Engineering, Graduate SchoolKookmin UniversitySeoulKorea
  2. 2.School of Mechanical Engineering and Department of Integrative Biomedical Science and Engineering, Graduate SchoolKookmin UniversitySeoulKorea

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