Journal of Shanghai Jiaotong University (Science)

, Volume 17, Issue 6, pp 712–716

Preparation and characterization of a novel hybrid copolymer hydrogel with poly(ethylene glycol) dimethacrylate, 2-hydroxyethyl methacrylate and layered double hydroxides

  • Pei Wang (王沛)
  • Zhi-yong Wei (魏志勇)
  • Jiang Cheng (程江)
  • Lian Liu (刘炼)
Article

DOI: 10.1007/s12204-012-1351-4

Cite this article as:
Wang, P., Wei, Z., Cheng, J. et al. J. Shanghai Jiaotong Univ. (Sci.) (2012) 17: 712. doi:10.1007/s12204-012-1351-4

Abstract

This paper describes the fabrication, characterization and properties of a novel hybrid poly(ethylene glycol) (PEG) based hydrogel via in situ polymerization. The hybrid hydrogel was fabricated by free-radical redox polymerization using ammonium persulfate (APS) and N, N, N′, N′-tetramethylethylenediamine (TEMED) as initiators and N, N′-methylene bisacrylamide (BIS) as cross-linker at 60°C. To create a hybrid hydrogel, 0.2% (mass fraction) of MgAl layered double hydroxide (LDH) was added to the aqueous solution by ultrasonic dispersion. The physicochemical properties of hybrid hydrogel under vacuum freeze-drying processing were characterized by Fourier transform infrared (FTIR) spectroscopy, thermal gravimetric analysis (TGA) and scanning electron microscopy (SEM), while swelling kinetics and gel content were calculated. Swelling degree in distilled water varied from 94%–125% with a gel mass fraction of 83%–91%. SEM images showed that the micron pore size of hydrogel could be adjusted within the range of several micrometers by changing the cross-linker mass fraction from 2% to 10% (based on glycol). The results showed that the hybrid hydrogels exhibited excellent physicochemical behavior and might be a promising material for applications in tissue engineering and drug delivery.

Key words

poly(ethylene glycol) (PEG) based hydrogel poly(ethylene glycol) dimethacrylate 2-hydroxyethyl methacrylate layered double hydroxide in situ polymerization 

CLC number

TQ 31 

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Copyright information

© Shanghai Jiaotong University and Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Pei Wang (王沛)
    • 1
  • Zhi-yong Wei (魏志勇)
    • 2
  • Jiang Cheng (程江)
    • 1
  • Lian Liu (刘炼)
    • 1
  1. 1.Department of Materials Science and EngineeringDalian Maritime UniversityDalianLiaoning, China
  2. 2.School of Automotive EngineeringDalian University of TechnologyDalianLiaoning, China

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