Establishment of sustainable health science for future generations: from a hundred years ago to a hundred years in the future
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Recently, we have investigated the relationship between environment and health from a scientific perspective and developed a new academic field, “Sustainable Health Science” that will contribute to creating a healthy environment for future generations. There are three key points in Sustainable Heath Science. The first key point is “focusing on future generations”—society should improve the environment and prevent possible adverse health effects on future generations (Environmental Preventive Medicine). The second key point is the “precautious principle”. The third key point is “transdisciplinary science”, which means that not only medical science but also other scientific fields, such as architectural and engineering science, should be involved. Here, we introduce our recent challenging project “Chemiless Town Project”, in which a model town is under construction with fewer chemicals. In the project, a trial of an education program and a health-examination system of chemical exposure is going to be conducted. In the future, we are aiming to establish health examination of exposure to chemicals of women of reproductive age so that the risk of adverse health effects to future generations will decrease and they can enjoy a better quality of life. We hope that society will accept the importance of forming a sustainable society for future generations not only with regard to chemicals but also to the whole surrounding environment. As the proverb of American native people tells us, we should live considering the effects on seven generations in the future.
KeywordsSustainable health science Environmental preventive medicine Future generations Precautious principle Chemiless Town Project
In modern society, people enjoy healthy and a convenient life style with highly developed technology. On the other hand, rapid economic growth based on mass production, mass consumption, and mass disposal has caused global environmental problems and health disorders originating in the environment [1, 2, 3, 4, 5].
People have taken action about the global environmental problems such as global warming, global pollution, and ozone layer depletion. Therefore, scientists have established “Sustainability Science” [6, 7] in order to improve global environmental problems. However, sufficient action on medical problems caused by environmental factors has not yet been taken in Japan or in the world. It is extremely important to study the relationship between the environment and children’s health [8, 9, 10], and to improve environment so that we can sustain the health of children and future generations.
Japan has experienced tragic environmental diseases such as Minamata disease  and Itai–Itai (ouch–ouch) disease  in the history in the process of economic growth. From the experience, Japan at present has strict regulations with regard to environmental pollution. However, the target of current medical science is the human population who are living the modern society. If the target is the people living currently, it cannot necessarily protect future generations’ health.
Therefore, we propose establishing “Sustainable Health Science”, that is a new public health focusing on future generations. To protect the future generations’ health, it is necessary that multi-disciplinary scientists gather and establish transdisciplinary “Sustainable Health Science”.
Here, we introduce the background, the concept, and our recent activity in “Sustainable Health Science” focusing on children's and future generations’ health.
The background to the establishment of “Sustainable Health Science”
About 100 years ago, many people lost their lives because of malnutrition or infectious diseases in Japan. This period can be regarded as an “era of enlightenment of public health” in Japan. The first textbook of public health in the Japanese language was published by Mori and Koike in 1897 . In those days, the mission of public health was to protect the current generation’s human health and to promote it. Therefore, they took action on social infrastructure such as sewage planning and town planning, etc.
In the past 50 years, mass production, mass consumption, and mass waste as a result of rapid economic growth have caused several environmental problems and diseases related to environmental factors [5, 11]. In order to improve global environmental problems such as global warming, global pollution, and ozone layer depletion, the study of “Sustainability Science” was started [6, 7]. Sustainability Science involves application of multiple fields of science to attain a sustainable society. The basic concept of Sustainability Science can be found in a proverb of North American native people, which is “In our every deliberation, we must consider the impact of our decisions on the next seven generations”. An academic field related to Sustainability Science is one of the most important introduced in the twenty-first century and it should be rapidly developed.
On the other hand, current medical problems caused by environmental factors have not yet been studied and action enough taken. Obviously, our life-style has changed dramatically in the past 50 years and, unlike the old days, we are surrounded by uncountable artificial chemicals in daily life [4, 5, 14]. It is time for us to stop and rethink current use of chemicals and the need to sustain health by improving the environment. From past experience, Japan at present has strict regulations with regard to environmental pollution. However, the target of current medical science is the humans who are living in modern society. If the target is modern people, it cannot necessarily protect future generations’ health, since fetuses are at the most susceptible period in human life stage and higher attention should be paid.
Therefore, we propose the establishment of “Sustainable Health Sciences” which is new preventive medicine or public health focusing on future generations.
The concept of “Sustainable Health Science”
One hundred years ago, the concept of public health was to protect the current generation’s health. Now, we need to establish the new public health, focusing on 100 years in the future.
In modern society, people are exposed to uncountable chemicals [4, 5, 14], however, only for a handful of chemicals are we clear about their health effects on humans. Almost nothing is clear about the relationship between multiple chemical exposure and human health, especially the effect on children and fetuses [4, 8, 9, 10, 14]. Our previous studies revealed that fetuses in Japan were contaminated by multiple chemicals that are transferred through the umbilical cord from their mothers [4, 14, 15, 16]. Most of the chemicals which were detected from the umbilical cords of newborn babies did not exist until 100 years ago, and there is no scientific proof that there is no risk of those mixtures of chemicals to human health.
As a result of our studies on the health effect of environmental chemicals, we have tried to find a way to solve the problem fundamentally [4, 14, 15, 16], and have suggested reduction of the chemicals in the environment to prevent possible adverse health effects [17, 18, 19, 20, 21, 22]. We call it “Environmental Preventive Medicine (EPM)”. In medical science, preventive medicine is about persuading people to inform themselves about their own health situation and leading them to take action by themselves. However, the adverse health effects of environmental pollution cannot be prevented by personal effort, especially the effect on fetuses or future generations. Therefore, society should be improved.
Here, we suggest establishing a new field of science at which society should aim in the twenty-first century—“Sustainable Health Science”.
Our recent activity as an example of “Sustainable Health Science” using a “Chemiless Town”, an education program, and health examination
To solve the problem of multiple chemical contamination of future generations, fundamentally we suggest building a town with only necessary amounts of chemicals. In modern society, humans enjoy healthy and long life because of the development of the chemical industry in a sense. However, on the other hand, too many unnecessary numbers and amounts of artificial chemicals might have caused modern sickness and diseases such as child allergy, bronchitis, and asthma .
Chemiless Town Project to prevent sick building syndrome
There is concern about the adverse health effects of various chemicals from building materials to humans, especially to children . Since most people stay indoors, for example in private houses, schools, or office buildings, greater attention should be paid to indoor air quality. Newborn babies, especially, are in a house almost 24 h a day, and fetuses are influenced strongly by mothers’ surrounding environment.
Currently, about 10% of the Japanese population is reported to be sensitive to, or to actually show symptoms induced by, chemicals in indoor air ; this is called “sick-building syndrome (SBS)” . SBS is a series of symptoms, for example dizziness, headache, asthma, and throat ache, caused by volatile organic compounds (VOCs) in newly constructed or reformed buildings. It is also caused by newly purchased furniture. It is also called as “Sick-house syndrome” in Japan, and if it happens in school, it is called “Sick-school syndrome”.
In Japan, indoor air quality is now regulated by national law. However, it only applies to formaldehyde and chlorpyrifos . Formaldehyde must be below 0.08 ppm and use of chlorpyrifos is, basically, prohibited. Obviously, regulation of formaldehyde alone is not enough to improve the symptoms or to prevent them.
The number of patients suffering from the syndrome is increasing, and urgent management of harmful chemicals is required. However, it is extremely difficult to find what chemicals actually cause the syndrome. It is not practical to find the cause one by one and take actions against to each chemical because the number of chemicals in indoor air is uncountable.
However, people can live healthily as long as there are no chemicals causing sickness. SBS occurs only when problematic chemicals exist in indoor air. As the first target sickness to which we can apply EPM, we chose SBS, because it seemed to be easier to approach because the problem occurs only inside buildings.
We have tried to apply EPM as a strategic method, and are now building a model town on the university campus. In the model town, houses and buildings are built with materials containing as few chemicals as possible, and it is called ‘‘Chemiless Town’’ .
So far, we have analyzed and calculated the amounts of chemicals existing in the indoor air of houses and a building in Chemiless Town, and are trying to identify the sources of problematic volatile chemicals by applying a points scale. Also, at the same time, we are evaluating air quality by using healthy volunteers . It has become clear that if total VOC are lower, the number of people who claim the symptoms clearly decrease.
Our goal is to build the town as a sustainable health town and people can enjoy better quality of life there. Also, we would like to spread this concept and suggest building “Chemiless Town” in many places in Japan and the world.
An attempt to introduce an educational program of Sustainable Health Science
Because sustainable health science is a quite new concept, there are almost no teachers or lecturers who can teach citizens. It is necessary to educate young people who can teach the concept in the educational field. Therefore, we started a trial graduate program as a Master’s and Doctor’s course. This course provides past and recent findings and knowledge about the relationship between environment and human health, and new preventive medicine and public health focusing on future generations. Students are required to be able to communicate in English and participate in group discussion.
Health examination of chemical exposure
In public health, it is quite important that people know about themselves. For example, to prevent diabetes or hypertension [31, 32], they go for health examination and they know what blood pressure they have, what is their heart status, they will know if their blood sugar level is high or low. Only if they know their health status, will they take action. Of course, even if they know their health status, many people do not take action and unfortunately the health status of those people usually becomes worse. Therefore, when they go through health examination, it is necessary that medical and co-medical staff intervene in the possible patient’s life, and stimulate their activities such as sports, walking, food control, etc.
In the field of EPM, it is necessary that people know their own contamination level by chemicals. Currently, there is no clinic or hospital where people can receive a health examination of chemical exposure. In Chemiless-Town, there is “Clinic for Environmental Medicine”, and there is a system that people can receive health examination by blood sampling. In the system, PCBs are used as the representative chemicals to assess the concentration level of persistent chemicals such as organic agricultural insecticides and dioxins because many persistent organic chlorinated chemicals have a strong correlation with PCBs .
If the level of contamination is high, intervention in life style is practiced, such as advising him/her to avoid eating the gut of fish. If the level of contamination is very high, medication can be applied. An anion-exchange resin with an imidazolium salt on an epoxide polymer skeleton is pharmacologically useful in reducing PCBs and dioxins [19, 20, 22].
Rapid economic growth has caused health disorders originating in the environment. The twenty-first century is thought to be an era of preventive medicine. Recently, we have investigated the relationship between environment and health from a scientific perspective and have developed a new academic field, “Sustainable Health Science” that will contribute to the creation of a healthy environment for future generations.
In this paper, we introduced our recent challenging project the “Chemiless Town Project”, in which a model town is under construction with fewer chemicals. In the project, a trial of an education program to produce leaders who can teach sustainable health science is being conducted. Furthermore, a health-examination system to assess exposure to chemicals is going to be established, because it is very important to change people by letting them know about their own contamination level. In the future, we are aiming to establish health examination to assess the exposure to chemicals of women of reproductive age so that the risk of adverse health effects to future generations will decrease and they can enjoy better quality of life.
Using the results from the project, we will spread our idea worldwide about the need for sustainable health science for future generations from the viewpoint of EPM, because multiple contamination of future generations is not confined solely to Japan.
We hope that society will recognize the importance of forming a sustainable society for future generations not only with regard to chemicals, but also the whole surrounding environment. As the proverb of American native people shows us, we should live considering the effects on seven generations in the future.
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