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Maximum distance in single-isocenter technique of stereotactic radiosurgery with rotational error using margin-based analysis

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Abstract

Through geometrical simulation, we evaluated the effect of rotational error in patient setup on geometrical coverage and calculated the maximum distance between the isocenter and target, where the clinical PTV margin secures geometrical coverage with a single-isocenter technique. We used simulated spherical GTVs with diameters of 1.0 (GTV 1), 1.5 (GTV 2), 2.0 (GTV 3), and 3.0 cm (GTV 4). The location of the target center was set such that the distance between the target and isocenter ranged from 0 to 15 cm. We created geometrical coverage vectors so that each target was entirely covered by 100% of the prescribed dose. The vectors of the target positions were simultaneously rotated within a range of 0°–2.0° around the x-, y-, and z-axes. For each rotational error, the reduction in geometrical coverage of the targets was calculated and compared with that obtained for a rotational error of 0°. The tolerance value of the geometrical coverage reduction was defined as 5% of the GTV. The maximum distance that satisfied the 5% tolerance value for different values of rotational error at a clinical PTV margin of 0.1 cm was calculated. When the rotational errors were 0.5° for a 0.1 cm PTV margin, the maximum distances were as follows: GTV 1: 7.6 cm; GTV 2: 10.9 cm; GTV 3: 14.3 cm; and GTV 4: 21.4 cm. It might be advisable to exclude targets that are > 7.6 cm away from the isocenter with a single-isocenter technique to satisfy the tolerance value for all GTVs.

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Acknowledgements

This research was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI grant no. 19K17227.

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Authors and Affiliations

  1. Department of Radiation Oncology, Niigata University Medical and Dental Hospital, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Japan

    Hisashi Nakano, Satoshi Tanabe, Takeshi Takizawa, Madoka Sakai, Toshimichi Nakano, Hirotake Saito & Atsushi Ohta

  2. Section of Radiology, Department of Clinical Support, Niigata University Medical and Dental Hospital, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Japan

    Takumi Yamada & Hironori Sakai

  3. Department of Radiological Technology, Niigata University Graduate School of Health Sciences, 2-746 Asahimachi-dori, Chuo-ku, Niigata, Japan

    Satoru Utsunomiya & Ryuta Sasamoto

  4. Department of Radiation Oncology, Niigata Neurosurgical Hospital, Yamada, Nishi-ku, Niigata, 3057, Japan

    Takeshi Takizawa

  5. Department of Radiology and Radiation Oncology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Japan

    Motoki Kaidu & Hiroyuki Ishikawa

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  1. Hisashi Nakano
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Correspondence to Hisashi Nakano.

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Nakano, H., Tanabe, S., Yamada, T. et al. Maximum distance in single-isocenter technique of stereotactic radiosurgery with rotational error using margin-based analysis. Radiol Phys Technol 14, 57–63 (2021). https://doi.org/10.1007/s12194-020-00602-2

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  • DOI: https://doi.org/10.1007/s12194-020-00602-2

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