Radiological Physics and Technology

, Volume 1, Issue 2, pp 196–200 | Cite as

Customization of normal data base specific for 3-tesla MRI is mandatory in VSRAD analysis

  • Masami Goto
  • Yuuichi Suzuki
  • Osamu Abe
  • Naoto Hayashi
  • Shigeki Aoki
  • Harushi Mori
  • Tomohiko Masumoto
  • Yasushi Watanabe
  • Yoshirou Satake
  • Kenji Ino
  • Keiichi Yano
  • Kyouhito Iida
  • Kazuo Mima
  • Kuni Ohtomo
Article
  • 118 Downloads

Abstract

A voxel-based specific regional analysis system for Alzheimer’s disease (VSRAD) was used for quantitative analysis of parahippocampal atropy with 1.5-tesla (T) MRI in a voxel-wise manner. The analysis of images acquired under a different imaging condition provides an error factor that has a calculated value. Clinical application of 3T-MRI is necessary for establishing a normal data base (N-DB) specific for 3T-MRI data, which permits appropriate application of VSRAD. We established an N-DB specific for 3T-MRI for use in VSRAD. The “Z-score of the parahippocampal gyrus” was 0.79 ± 0.32, and the N-DB of each age group did not have a big deflection when we analyzed a group of physically unimpaired persons in an N-DB specific for 3T-MRI. Therefore, we were able to confirm the validity of the customized N-DB. The “Z-score of the parahippocampal gyrus” was 1.62 ± 0.47 for the N-DB of VSRAD. The numerical value was high for the group of physically unimpaired persons.

Keywords

Hippocampus Central nervous system Magnetic resonance imaging (MRI) Voxel-based morphometry (VBM) Alzheimer’s disease Voxel-based specific regional analysis system for Alzheimer’s disease (VSRAD) 

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Copyright information

© Japanese Society of Radiological Technology and Japan Society of Medical Physics 2008

Authors and Affiliations

  • Masami Goto
    • 1
  • Yuuichi Suzuki
    • 1
  • Osamu Abe
    • 2
  • Naoto Hayashi
    • 2
  • Shigeki Aoki
    • 2
  • Harushi Mori
    • 2
  • Tomohiko Masumoto
    • 2
  • Yasushi Watanabe
    • 1
  • Yoshirou Satake
    • 1
  • Kenji Ino
    • 1
  • Keiichi Yano
    • 1
  • Kyouhito Iida
    • 1
  • Kazuo Mima
    • 1
  • Kuni Ohtomo
    • 2
  1. 1.Department of Radiological TechnologyUniversity of Tokyo HospitalTokyoJapan
  2. 2.Department of RadiologyUniversity of Tokyo HospitalTokyoJapan

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