Chronic adult primary immune thrombocytopenia (ITP) in the Asia-Pacific region

  • Lee Lai Heng
  • Priscilla Caguioa
  • Ng Soo Chin
  • Tzeon-Jye Chiou
  • Jong Wook Lee
  • Yoshitaka Miyakawa
  • Karmel L. Tambunan
  • Beng H. Chong
Review Article

Abstract

Patients with primary immune thrombocytopenia (ITP) from the Asia-Pacific region often exhibit characteristics distinct from those of patients from the West. Moreover, as the region itself is heterogeneous, the ITP landscape among individual Asia-Pacific countries can be diverse. The recently released international consensus report on ITP places new emphasis on ITP, but does not address the unique ITP landscape in the Asia-Pacific region, which is home to 60% of the world’s population. In an attempt to characterize how the ITP landscape differs between the West and the Asia-Pacific region, an expert panel with representatives from Northeast Asia, Southeast Asia, and Australia was convened. Important differences were identified between the guidance provided in the international consensus report and experience in the Asia-Pacific region, namely diagnostic practices, incidence and approach to ITP secondary to H. pylori infection, systemic lupus erythematosus-related ITP, the use of bone marrow examination, initial treatment strategies, and the role of splenectomy, rituximab, and thrombopoietin receptor agonists.

Keywords

Asia-Pacific region Primary immune thrombocytopenia (ITP) 

Copyright information

© The Japanese Society of Hematology 2011

Authors and Affiliations

  • Lee Lai Heng
    • 1
  • Priscilla Caguioa
    • 2
  • Ng Soo Chin
    • 3
  • Tzeon-Jye Chiou
    • 4
    • 5
  • Jong Wook Lee
    • 6
  • Yoshitaka Miyakawa
    • 7
  • Karmel L. Tambunan
    • 8
  • Beng H. Chong
    • 9
  1. 1.Singapore General HospitalSingaporeSingapore
  2. 2.University of Stanto Tomas HospitalManilaPhilippines
  3. 3.Sime Darby Medical CentreSubang JayaMalaysia
  4. 4.Taipei Veterans General Hospital, National Young-Ming University School of Medicine, National Defense Medical CenterTaipeiTaiwan
  5. 5.Hematology Society of TaiwanTaipeiTaiwan
  6. 6.The Catholic University of Korea, Seoul St. Mary’s HospitalSeoulKorea
  7. 7.Keio UniversityTokyoJapan
  8. 8.University of IndonesiaJakartaIndonesia
  9. 9.St George Clinical SchoolUniversity of New South Wales, St George HospitalSydneyAustralia

Personalised recommendations