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International Journal of Hematology

, Volume 92, Issue 3, pp 535–537 | Cite as

Bullous exudative retinal detachment due to infiltration of leukemic cells in a child with acute lymphoblastic leukemia

  • Kenichi Yoshida
  • Daisuke Hasegawa
  • Ayako Takusagawa
  • Itaru Kato
  • Chitose Ogawa
  • Nariaki Echizen
  • Kishiko Ohkoshi
  • Tatsuo Yamaguchi
  • Ryota Hosoya
  • Atsushi ManabeEmail author
Case Report

Abstract

Acute lymphoblastic leukemia (ALL) is known to cause several ocular involvements, but exudative retinal detachment is a rare complication. We describe a case report of a 4-year-old boy with T cell ALL who developed bilateral exudative retinal detachment caused by leukemic infiltration in the retinas after achieving hematological remission. Intravenous steroid pulse therapy and local irradiation reversed the condition, but it recurred concurrently with disease progression after a second relapse in the bone marrow. It is suggested that ophthalmic examination is crucial for ALL patients, especially for those whose white blood cell count is very high at onset.

Keywords

Acute lymphoblastic leukemia Children Retinal detachment Aspiration of subretinal fluid 

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Copyright information

© The Japanese Society of Hematology 2010

Authors and Affiliations

  • Kenichi Yoshida
    • 1
  • Daisuke Hasegawa
    • 1
  • Ayako Takusagawa
    • 1
  • Itaru Kato
    • 1
  • Chitose Ogawa
    • 1
  • Nariaki Echizen
    • 2
  • Kishiko Ohkoshi
    • 2
  • Tatsuo Yamaguchi
    • 2
  • Ryota Hosoya
    • 1
  • Atsushi Manabe
    • 1
    Email author
  1. 1.Department of PediatricsSt. Luke’s International HospitalTokyoJapan
  2. 2.Department of OphthalmologySt. Luke’s International HospitalTokyoJapan

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