International Journal of Hematology

, Volume 89, Issue 3, pp 348–351 | Cite as

Intravascular large B-cell lymphoma with involvement of the abdominal subcutis: a case report and literature review

  • Wenjuan Yin
  • Min Li
  • Zifen Gao
  • Fanzhou Huang
  • Jiping Da
  • Cuiling Liu
Case Report
First Online:
Received:
Revised:
Accepted:

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma (DLBCL). It commonly presents with a variety of symptoms due to occlusion of small vessels by tumor cells in different organ systems. Clinically patients may present with generalized symptoms such as fever and malaise. In western patients, there is a ‘cutaneous variant’ of IVLBCL, which demonstrates cutaneous involvement only. However, Asian patients show hemophagocytosis, which is typical of the ‘Asian variant’. Here we report a case of IVLBCL in a Chinese individual who presented with a huge mass in the subcutis of the abdomen.

Keywords

Intravascular lymphoma Cutaneous variant Asian variant 
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Notes

Acknowledgments

We would like to thank Dr. Michael A. McNutt for reviewing and correcting the manuscript.

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Copyright information

© The Japanese Society of Hematology 2009

Authors and Affiliations

  • Wenjuan Yin
    • 1
  • Min Li
    • 1
  • Zifen Gao
    • 1
  • Fanzhou Huang
    • 2
  • Jiping Da
    • 3
  • Cuiling Liu
    • 1
  1. 1.Department of PathologyPeking University Health Science CenterBeijingChina
  2. 2.Department of HematologyPeking University China-Japan Friendship HospitalBeijingChina
  3. 3.Department of PathologyPeking University China-Japan Friendship HospitalBeijingChina

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