Three-dimensional spectral-domain optical coherence tomography of melanocytoma of the optic nerve head

  • Sandeep SaxenaEmail author
  • Bhumika Sharma
  • Shashi K. Bhasker


Melanocytoma of the optic nerve head is a benign melanocytic lesion that usually occurs in the inferotemporal area of the optic nerve head. The uveal melanocytes emanating from the neural crest during embryogenesis are believed to be the cells of origin. These cells are present in the lamina choroidalis, the portion of the optic nerve adjacent to the choroid. The tumor is typically unilateral and stationary and rarely undergoes a malignant transformation. The condition is usually asymptomatic except when the tumor undergoes extensive necrosis or malignant transformation or is associated with the choroidal neovascular membrane [1]. Shields et al. [2] described that melanocytoma, although benign, has the capacity to cause significant visual morbidity. They reported that at 10 and 20 years, respectively 18% and 33% will lose two or more lines of vision by Kaplan–Meier estimates.

Spectral-domain optical coherence tomography (OCT) is increasingly being used in various retinal...


Optic Nerve Optical Coherence Tomography Retinal Pigment Epithelium Retinal Nerve Fiber Layer Optic Nerve Head 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

(AVI 145,203 kb)


  1. 1.
    Shah VA, Vincent RD, Desai K, Gallimore G, Rupani M. Documentation of optic disc melanocytoma by spectral and time domain optical coherence tomography. Can J Ophthalmol. 2009;44:603–4.PubMedCrossRefGoogle Scholar
  2. 2.
    Shields JA, Demirci H, Mashayekhi A, Shields CL. Melanocytoma of optic disc in 115 cases: the 2004 Samuel Johnson Memorial Lecture, part 1. Ophthalmology. 2004;111:1739–46.PubMedGoogle Scholar
  3. 3.
    Saxena S, Singh K. Three-dimensional retinal imaging in spectral domain optical coherence tomography. In: Saxena S, Sadda S, editors. Emerging technologies in retinal diseases. New Delhi: Jaypee Medical Publishers; 2009. p. 67–122.CrossRefGoogle Scholar
  4. 4.
    Byrne SF, Grenn RL. Ultrasound of the eye and orbit. Second edn. Mosby 2002; 115–122, 151–152.Google Scholar
  5. 5.
    Shields CL, Perez B, Benavides R, Materin MA, Shields JA. Optical coherence tomography of optic disc melanocytoma in 15 cases. Retina. 2008;28:441–6.PubMedCrossRefGoogle Scholar
  6. 6.
    De Potter P, Shields CL, Eagle RC, Shields JA, Lipkowitz JL. Malignant melanoma of the optic nerve. Arch Ophthalmol. 1996;114:608–12.PubMedCrossRefGoogle Scholar
  7. 7.
    Shields JA, Demirci H, Mashayekhi A, Eagle RC, Shields CL. Melanocytoma of the optic disc. a review. Sur Ophthalmol. 2006;51:93–104.CrossRefGoogle Scholar
  8. 8.
    Chaudhary R, Arora R, Mehta DK, Singh M. Optical coherence tomography study of optic disc melanocytoma—case report. Ophthalmic Surg Lasers Imaging. 2006;37:58–61.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Sandeep Saxena
    • 1
    Email author
  • Bhumika Sharma
    • 1
  • Shashi K. Bhasker
    • 1
  1. 1.Department of OphthalmologyC.S.M. Medical University (Erstwhile King George’s Medical University)LucknowIndia

Personalised recommendations