Biomarker Testing and Pre-emptive Therapy in Preventing Heart Failure
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In an attempt to reduce the heart failure epidemic, screening and prevention will become an increasing focus of management in the wider at-risk population. Refining risk prediction through the use of biomarkers in isolation or in combination is emerging as a critical step in this process. The utility of biomarkers to identify disease manifestations before the onset of symptoms and detrimental myocardial damage is proving to be valuable. In addition, biomarkers that predict the likelihood and rate of disease progression over time will help streamline and focus clinical efforts and therapeutic strategies. Importantly, several recent early intervention studies using biomarker strategies are promising and indicate that not only can new-onset heart failure be reduced but also the development of other cardiovascular conditions.
KeywordsBiomarkers Heart failure Cardiovascular disease prediction and prevention
This work was supported by the European Commission FP7 project FIBRO-TARGETS and HOMAGE and the Health Research Board of Ireland [grant numbers 602904; 305507; CSA-2012-36, respectively].
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Conflict of Interest
Chris Watson, Mark Ledwidge, Ken McDonald and Joe Gallagher have no relevant disclosures to report.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by the author.
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