Vitamin D, Hypertension, Left Ventricular Hypertrophy, and Diastolic Dysfunction


DOI: 10.1007/s12170-011-0175-3

Cite this article as:
Nigwekar, S.U., Bhan, I. & Thadhani, R. Curr Cardiovasc Risk Rep (2011) 5: 314. doi:10.1007/s12170-011-0175-3


The extra-skeletal effects of vitamin D have been increasingly recognized in the recent years and its effects on blood pressure and cardiac function are areas of active investigation. This article reviews the current state of knowledge about vitamin D with respect to blood pressure and left ventricular hypertrophy. Potential biological mechanisms implicated in linking vitamin D deficiency with hypertension and cardiac dysfunction are outlined along with data from both observational and randomized controlled trials on this topic.


Vitamin D Hypertension Systolic blood pressure Diastolic blood pressure Left ventricular hypertrophy 

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Division of NephrologyMassachusetts General HospitalBostonUSA

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