The neurobiology and treatment of tobacco dependence
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Abstract
Tobacco dependence is a major cause of preventable morbidity and mortality in the United States. Smoking cessation significantly reduces these health consequences. Many smokers want to stop smoking, but few succeed because of the chronic, relapsing nature of nicotine addiction. However, with our growing understanding of the neural effects of nicotine, many effective therapeutic options have been developed and become clinically available. This article summarizes the latest data on the epidemiology, neurobiology, and pharmacotherapies for the treatment of tobacco dependence.
Keywords
Nicotine Smoking Cessation Ventral Tegmental Area Bupropion Nicotine Dependence
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