Current Cardiovascular Risk Reports

, Volume 1, Issue 4, pp 303–309 | Cite as

Low-molecular-weight heparin use in acute coronary syndromes and percutaneous coronary interventions: An update

  • Jeffrey J. Link
  • John J. Warner
  • James A. de Lemos


Based on important studies published in the past year, the role of low-molecular-weight heparin in acute coronary syndromes and percutaneous coronary interventions has continued to evolve. For patients with non-ST-elevation acute coronary syndromes, several alternatives to enoxaparin have been introduced, including fondaparinux and bivalirudin. In patients with ST-elevation myocardial infarction, recent studies have demonstrated a clear mortality benefit from adjunctive antithrombin therapy and the superiority of a prolonged course of enoxaparin over a standard duration of unfractionated heparin. Furthermore, recent data have demonstrated the safety of enoxaparin as an alternative to unfractionated heparin among patients undergoing percutaneous coronary interventions.


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Copyright information

© Current Medicine Group LLC 2007

Authors and Affiliations

  • Jeffrey J. Link
  • John J. Warner
  • James A. de Lemos
    • 1
  1. 1.University of Texas Southwestern Medical CenterDallasUSA

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