Determination of Trace Sulfonamides in Environmental Water and Milk Through Capillary Electrochromatography Using PEG-MoS2 as Stationary Phase

  • Zhimin Cai
  • Xuan Wang
  • Jianxin An
  • Qiqi Zhang
  • Xiaotong Jin
  • Han Yin
  • Yutong Shao
  • Yuhong XiangEmail author
  • Nengsheng YeEmail author


In this work, a composite of polyethylene glycol (PEG) modified MoS2 (PEG-MoS2) was synthesized and used as the stationary phase of open-tubular capillary column via a chemical bonding strategy. The PEG-MoS2 exhibited a sphere-like architecture through characterization of scanning electronic microscopy. p-phenylenediboronic acid was introduced as a linker to combine the PEG-MoS2 with capillary column. A capillary electrochromatographic method was established for the determination of nine sulfonamides by using PEG-MoS2-coated capillary column. The intra-day, inter-day, and column-to-column relative standard deviations (RSDs) of migration time and peak area were in the range of 0.80–4.38% and 1.61–9.22%, respectively. The limits of detection were in the range of 20.4–64.8 ng/mL. The recoveries in environmental water and milk were from 83.26 to 116.29% and 80.86 to 118.22%. This work is the first report that PEG-MoS2 material is utilized as stationary phase for capillary electrochromatography.


Capillary electrochromatography Molybdenum disulfide Polyethylene glycol Sulfonamide 


Funding Information

This work was financially supported by the Beijing Natural Science Foundation (2162008).

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Standards

This article does not contain any studies with human participants performed by any of the authors.

Informed Consent

Informed consent is not applicable.

Supplementary material

12161_2019_1676_MOESM1_ESM.docx (25.2 mb)
ESM 1 (DOCX 25.2 MB)


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of ChemistryCapital Normal UniversityBeijingPeople’s Republic of China

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