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Food Analytical Methods

, Volume 12, Issue 3, pp 712–721 | Cite as

Extraction of Five Fluoroquinolones in Eggs by Magnetic Solid-Phase Extraction with Fe3O4–MoS2 and Determination by HPLC-UV

  • Hao WuEmail author
  • Yanli Liu
  • Jianzhong Chang
  • Bingxin Zhao
  • Yaoxing Huo
  • Zhuliang Wang
  • Yating Shi
Article
  • 38 Downloads

Abstract

Based on the synthesis of Fe3O4–MoS2 as magnetic solid-phase extraction adsorbent, a convenient, rapid, and effective method for extracting five fluoroquinolones (FQs) (lomefloxacin, ciprofloxacin, ofloxacin, sparfloxacin, and enrofloxacin) from eggs and detecting their contents by high-performance liquid chromatography using an ultraviolet-visible detector was established. The synthesized adsorbent was characterized by x-ray diffraction spectroscopy, scanning electron microscopy, and vibrating sample magnetometry. This study optimized the parameters (adsorbent, time of adsorption and desorption, eluent, sample solution, pH, and others) affecting the analytical performance of this method. Following optimization, the method provided good linearity from 2.5 to 300 μg L−1, correlation coefficients of determination from 0.9990 to 0.9997, limits of detection from 0.2 to 5.0 μg L−1, and limits of quantification from 0.7 to 17 μg L−1. The intra- and interday RSDs were less than 5%. The range of the spiked recoveries of FQs in eggs was 88.6 to 96.6%, and the RSDs were less than 5%.

Keywords

Fluoroquinolones High-performance liquid chromatography Magnetic solid-phase extraction Eggs 

Notes

Compliance with Ethical Standards

Conflict of Interest

Hao Wu declares that he has no conflict of interest. Yanli Liu declares that she has no conflict of interest. Jianzhong Chang declares that he has no conflict of interest. Bingxin Zhao declares that she has no conflict of interest. Yaoxing Huo declares that he has no conflict of interest. Zhuliang Wang declares that he has no conflict of interest. Yating Shi declares that she has no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animas performed by any of the authors.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Supplementary material

12161_2018_1404_MOESM1_ESM.docx (616 kb)
ESM 1 (DOCX 616 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.School of Chemistry and Materials Science of Shanxi Normal University & Key Laboratory of Magnetic Molecules and Magnetic Information Materials of Ministry of EducationLinfenChina
  2. 2.Research Institute of Materials Science of Shanxi Normal University & Collaborative Innovation Center for Shanxi Advanced Permanent Magnetic Materials and TechonologyLinfenChina
  3. 3.Comprehensive Inspection and Testing Center in Yaodu DistrictLinfenChina

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