Annals of Behavioral Medicine

, Volume 49, Issue 2, pp 165–176

Randomized Controlled Trial of Qigong/Tai Chi Easy on Cancer-Related Fatigue in Breast Cancer Survivors

  • Linda K. Larkey
  • Denise J. Roe
  • Karen L. Weihs
  • Roger Jahnke
  • Ana Maria Lopez
  • Carol E. Rogers
  • Byeongsang Oh
  • Jose Guillen-Rodriguez
Original Article

DOI: 10.1007/s12160-014-9645-4

Cite this article as:
Larkey, L.K., Roe, D.J., Weihs, K.L. et al. ann. behav. med. (2015) 49: 165. doi:10.1007/s12160-014-9645-4



Many breast cancer survivors experience fatigue, mood, and sleep disturbances.


This study aims to compare a meditative movement practice, Qigong/Tai Chi Easy (QG/TCE) with sham Qigong (SQG), testing effects of meditation/breath aspects of QG/TCE on breast cancer survivors’ persistent fatigue and other symptoms.


This double-blind, randomized controlled trial tested 12 weeks of QG/TCE versus SQG on fatigue, depression, and sleep among 87 postmenopausal, fatigued breast cancer survivors, stages 0–III, age 40–75.


Fatigue decreased significantly in the QG/TCE group compared to control at post-intervention (p = 0.005) and 3 months follow-up (p = 0.024), but not depression and sleep quality. Improvement occurred over time for both interventions in depression and sleep quality (all p < 0.05).


QG/TCE showed significant improvement over time compared to SQG for fatigue, but not depression or sleep. Both QG/TCE and SQG showed improvement for two prevalent symptoms among breast cancer survivors, depression and sleep dysfunction.


Fatigue Qigong Tai Chi Breast neoplasm Survivor symptoms 

Supplementary material

12160_2014_9645_MOESM1_ESM.docx (29 kb)
ESM 1DOCX 28.6 kb
12160_2014_9645_MOESM2_ESM.docx (43 kb)
ESM 2DOCX 43.2 kb

Copyright information

© The Society of Behavioral Medicine 2014

Authors and Affiliations

  • Linda K. Larkey
    • 1
    • 2
  • Denise J. Roe
    • 3
  • Karen L. Weihs
    • 4
  • Roger Jahnke
    • 5
  • Ana Maria Lopez
    • 6
  • Carol E. Rogers
    • 7
  • Byeongsang Oh
    • 8
    • 9
  • Jose Guillen-Rodriguez
    • 6
  1. 1.College of Nursing & Health InnovationArizona State UniversityPhoenixUSA
  2. 2.Mayo Clinic Cancer CenterMayo ClinicScottsdaleUSA
  3. 3.Mel & Enid Zuckerman College of Public HealthUniversity of ArizonaTucsonUSA
  4. 4.Department of PsychiatryUniversity of ArizonaTucsonUSA
  5. 5.Institute of Integral Qigong and Tai ChiHealth Action IncorporatedSanta BarbaraUSA
  6. 6.Arizona Cancer CenterUniversity of ArizonaTucsonUSA
  7. 7.University of Oklahoma Health Sciences CenterOklahomaUSA
  8. 8.Sydney Medical SchoolUniversity of SydneySydneyAustralia
  9. 9.Harvard Medical SchoolHarvard UniversityBostonUSA

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