Behavioral Mediators of Treatment Effects in the Weight Loss Maintenance Trial
- First Online:
The Weight Loss Maintenance Trial tested strategies for maintenance of weight loss. Personal contact was superior to interactive technology and self-directed conditions.
We aimed to identify behavioral mediators of the superior effect of personal contact vs. interactive technology and of personal contact vs. self-directed arms.
Overweight/obese adults at risk for cardiovascular disease (n = 1,032) who lost at least 4 kg were randomized to personal contact, interactive technology, or self-directed. After 30 months, 880 participants had data on weight and behavioral strategies.
Reported increase of intake of fruits and vegetables and physical activity and more frequent self-weighing met criteria as mediators of the better outcome of personal contact vs. interactive technology. Increased intake of fruits and vegetables, more frequent self-weighing, and decreased dessert consumption were mediators of the difference between personal contact vs. self-directed.
Inducing changes in the identified behaviors might yield better outcomes in future weight loss maintenance trials.
(ClinicalTrials.gov number NCT00054925)
KeywordsObesity Weight maintenance Weight regain Behavioral strategies Mediators
- 1.National Institutes of Health/National Heart LaBI. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: The evidence report. Obesity Research 6, 51S-210S. 1998.Google Scholar
- 2.World Health Organization. Obesity: Preventing and managing the global epidemic. 2000.Google Scholar
- 12.Daniels MJ, Roy JA, Kim C, Hogan JW. Perri MG. Biometrics: Bayesian Inference for the causal effect of mediation; 2012.Google Scholar
- 22.Little RJA, Rubin DB. Statistical analysis with missing data. 2nd ed. New York: Wiley; 2002.Google Scholar