Annals of Behavioral Medicine

, Volume 44, Issue 3, pp 295–296 | Cite as

Discerning Whether and How Long-Chain, n-3 Fatty Acids Lower Blood Pressure: A Comment on Skulas-Ray et al.

Invited Commentary


Conflict of interest

The author has no conflict of interest to disclose.


  1. 1.
    Mozaffarian D, Wu JH. Omega-3 fatty acids and cardiovascular disease: Effects on risk factors, molecular pathways, and clinical events. J Am Coll Cardiol. 2011;58(20):2047-2067.PubMedCrossRefGoogle Scholar
  2. 2.
    Kromhout D, Giltay EJ, Geleijnse JM. n-3 fatty acids and cardiovascular events after myocardial infarction. N Engl J Med. 2010;363(21):2015-2026.PubMedCrossRefGoogle Scholar
  3. 3.
    Skulas-Ray AC, Kris-Etherton PM, Harris WS, West SG. Effects of marine-derived omega-3 fatty acids on systemic hemodynamics: A dose response study. Ann Behav Med. 2012; doi: 10.1007/s12160‐012‐9393‐2
  4. 4.
    Harris WS, Pottala JV, Sands SA, Jones PG. Comparison of the effects of fish and fish-oil capsules on the n 3 fatty acid content of blood cells and plasma phospholipids. Am J Clin Nutr. 2007;86(6):1621-1625.PubMedGoogle Scholar
  5. 5.
    Geleijnse JM, Giltay EJ, Grobbee DE, Donders AR, Kok FJ. Blood pressure response to fish oil supplementation: Metaregression analysis of randomized trials. J Hypertens. 2002;20(8):1493-1499.PubMedCrossRefGoogle Scholar
  6. 6.
    Liu JC, Conklin SM, Manuck SB, Yao JK, Muldoon MF. Long-chain omega-3 fatty acids and blood pressure. Am J Hypertens. 2011;24(10):1121-1126.PubMedCrossRefGoogle Scholar
  7. 7.
    Harbaugh MP, Manuck SB, Jennings JR, Conklin SM, Yao JK, Muldoon MF. Long-chain, n-3 fatty acids and physical activity—Independent and interactive associations with cardiac autonomic control. Int J Cardiol. 2012 (in press)Google Scholar
  8. 8.
    Ginty AT, Conklin SM. Preliminary evidence that acute long-chain omega-3 supplementation reduces cardiovascular reactivity to mental stress: A randomized and placebo controlled trial. Biol Psychol. 2012;89(1):269-272.PubMedCrossRefGoogle Scholar
  9. 9.
    Peoples GE, McLennan PL, Howe PR, Groeller H. Fish oil reduces heart rate and oxygen consumption during exercise. J Cardiovasc Pharmacol. 2008;52(6):540-547.PubMedCrossRefGoogle Scholar

Copyright information

© The Society of Behavioral Medicine 2012

Authors and Affiliations

  1. 1.Heart and Vascular InstituteUniversity of Pittsburgh School MedicinePittsburghUSA

Personalised recommendations