Annals of Behavioral Medicine

, Volume 42, Issue 1, pp 111–119

Sexual HIV Transmission and Antiretroviral Therapy: A Prospective Cohort Study of Behavioral Risk Factors Among Men and Women Living with HIV/AIDS

  • Seth C. Kalichman
  • Chauncey Cherry
  • Denise White
  • Miche’l Jones
  • Tamar Grebler
  • Moira O. Kalichman
  • Mervi Detorio
  • Angela M. Caliendo
  • Raymond F. Schinazi
Original Article



Using antiretroviral therapies for HIV prevention relies on patient adherence and avoidance of co-occurring sexually transmitted infections.


The objective of this study is to simultaneously examine HIV treatment adherence and sexual risks for HIV transmission.


This study is a prospective cohort of 201 men and 55 women diagnosed with HIV/AIDS infection.


A total of 32% men and 39% women engaged in unprotected intercourse with at least one HIV negative or unknown HIV status sex partner over 12 months. Nearly half (46%) of participants with HIV negative or unknown HIV status unprotected sex partners had detectable HIV viral load and were significantly more likely to have contracted a sexually transmitted infection since their HIV diagnosis. Individuals at higher risk for transmitting HIV were also less adherent to antiretroviral therapies.


Programs that aim to use antiretroviral therapies for HIV prevention require careful attention to adherence, sexually transmitted co-infections, and substance use.


HIV treatment for prevention Test and treat Sexual risk behavior HIV prevention Positive prevention 


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Copyright information

© The Society of Behavioral Medicine 2011

Authors and Affiliations

  • Seth C. Kalichman
    • 1
    • 4
  • Chauncey Cherry
    • 1
  • Denise White
    • 1
  • Miche’l Jones
    • 1
  • Tamar Grebler
    • 1
  • Moira O. Kalichman
    • 1
  • Mervi Detorio
    • 2
  • Angela M. Caliendo
    • 2
  • Raymond F. Schinazi
    • 3
  1. 1.University of ConnecticutStorrsUSA
  2. 2.Department of Pathology and Laboratory Medicine and Center for AIDS ResearchEmory University School of MedicineAtlantaUSA
  3. 3.Center for AIDS ResearchEmory University School of Medicine and Veterans Affairs Medical CenterAtlantaUSA
  4. 4.Department of PsychologyUniversity of ConnecticutStorrsUSA

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