Exercise Interventions for Cancer Survivors: A Meta-Analysis of Quality of Life Outcomes
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Exercise improves quality of life (QOL) in cancer survivors, although characteristics of efficacious exercise interventions for this population have not been identified.
The present meta-analysis examines the efficacy of exercise interventions in improving QOL in cancer survivors, as well as features that may moderate such effects.
Studies were identified and coded, and QOL effect sizes were calculated and analyzed for trends.
Overall, exercise interventions increased QOL, but this tendency depended to some extent on exercise and patient features. Although several features were associated with effect sizes, models revealed that interventions were particularly successful if they targeted more intense aerobic exercise and addressed women. These tendencies emerged over longer periods of time and were more prominent in studies with higher methodological quality.
Appropriately designed exercise interventions enhance QOL for cancer survivors and this pattern is especially evident for women. Limitations are discussed.
KeywordsCancer Oncology Exercise Behavioral interventions Quality of life Meta-analysis Exercise interventions Cancer survivors
This research was supported by University of Connecticut Research Foundation Grant 433527 to Blair T. Johnson and Linda B. Pescatello and facilitated by NIH grants F31MH080626 to Rebecca A. Ferrer and R01-MH58563 to Blair T. Johnson. We thank Michelle R. Warren for her feedback on prior versions of this manuscript.
Conflict of Interest Statement
The authors have no conflict of interest to disclose.
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