Annals of Nuclear Medicine

, Volume 27, Issue 9, pp 867–869 | Cite as

The promise and limits of PET texture analysis



Metabolic heterogeneity is a recognized characteristic of malignant tumors. Positron emission tomography (PET) texture analysis evaluated intratumoral heterogeneity in the uptake of 18F-fluorodeoxyglucose. There were recent evidences that PET textural features were of prognostic significance in patients with different solid tumors. Unfortunately, there are still crucial standardization challenges to transform PET texture parameters from their current use as research tools into the arena of validated technologies for use in oncology practice. Testing its generalizability, robustness, consistency, and limitations is necessary before implementing it in daily patient care.


Positron Emission Tomography Texture Feature Positron Emission Tomography Image Total Lesion Glycolysis Intratumoral Heterogeneity 


Conflict of interest

None declared.


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Copyright information

© The Japanese Society of Nuclear Medicine 2013

Authors and Affiliations

  • Nai-Ming Cheng
    • 1
    • 2
  • Yu-Hua Dean Fang
    • 1
  • Tzu-Chen Yen
    • 1
  1. 1.Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial HospitalChang Gung University College of MedicineTaipeiTaiwan
  2. 2.Department of Nuclear MedicineChang Gung Memorial HospitalKeelungTaiwan

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