Annals of Nuclear Medicine

, Volume 27, Issue 10, pp 942–950 | Cite as

Radio-guided sentinel lymph node identification by lymphoscintigraphy fused with an anatomical vector profile: clinical applications

  • A. Niccoli AsabellaEmail author
  • F. Antonica
  • M. A. Renna
  • D. Rubini
  • A. Notaristefano
  • A. Nicoletti
  • G. Rubini
Technical note



To develop a method to fuse lymphoscintigraphic images with an adaptable anatomical vector profile and to evaluate its role in the clinical practice.


We used Adobe Illustrator CS6 to create different vector profiles, we fused those profiles, using Adobe Photoshop CS6, with lymphoscintigraphic images of the patient. We processed 197 lymphoscintigraphies performed in patients with cutaneous melanomas, breast cancer or delayed lymph drainage.


Our models can be adapted to every patient attitude or position and contain different levels of anatomical details ranging from external body profiles to the internal anatomical structures like bones, muscles, vessels, and lymph nodes. If needed, more new anatomical details can be added and embedded in the profile without redrawing them, saving a lot of time. Details can also be easily hidden, allowing the physician to view only relevant information and structures. Fusion times are about 85 s. The diagnostic confidence of the observers increased significantly. The validation process showed a slight shift (mean 4.9 mm).


We have created a new, practical, inexpensive digital technique based on commercial software for fusing lymphoscintigraphic images with built-in anatomical reference profiles. It is easily reproducible and does not alter the original scintigraphic image. Our method allows a more meaningful interpretation of lymphoscintigraphies, an easier recognition of the anatomical site and better lymph node dissection planning.


Fusion Vector Planar Scintigraphy Clinical Adaptable Profile 



I certify that neither I nor any member of my immediate family has a material personal or financial relationship with any offeror, or to a direct competitor of any offeror under consideration by this proposal evaluation committee. I further certify that no other relationship, bias or ethical conflict exists which will prevent me from evaluating any proposal solely on its merits and in accordance with the Request for Proposal’s evaluation criteria. Furthermore, I agree to notify the Procurement Officer if my personal or financial relationship with one of the offerors is altered at any time during the evaluation process. If I am serving as the Procurement Officer of record I agree to advise my supervisor of any changes that could appear to represent a conflict of interest.


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Copyright information

© The Japanese Society of Nuclear Medicine 2013

Authors and Affiliations

  • A. Niccoli Asabella
    • 1
    Email author
  • F. Antonica
    • 1
  • M. A. Renna
    • 1
  • D. Rubini
    • 1
  • A. Notaristefano
    • 1
  • A. Nicoletti
    • 1
  • G. Rubini
    • 1
  1. 1.DIM, Unità di Medicina Nucleare-RadiodiagnosticaUniversità degli studi di BariBariItaly

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