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Annals of Nuclear Medicine

, Volume 27, Issue 1, pp 65–73 | Cite as

Dynamic sequence respiratory gated perfusion pulmonary SPECT without external tracking device

  • Kenta Sakaguchi
  • Makoto Hosono
  • Masakazu Otsuka
  • Kohei Hanaoka
  • Kimio Usami
  • Tatsuro Uto
  • Kazunari Ishii
Original Article

Abstract

Objective

The purpose of this study was to develop and evaluate a new method for respiratory gated pulmonary perfusion SPECT (RGPS) based on dynamic acquisition without using an external tracking device (ETD) or list-mode data acquisition.

Methods

In the phantom study, our method used a dynamic sequence technique, which was specified by sequences of 50-ms acquisition during 30 s per view of SPECT instead of using an ETD. For this purpose, we created a computer program that identified respiratory phases by calculating the center of activity (COA) in each dynamic frame image. We compared RGPS using the dynamic sequence acquisition (RGPS-DS) and RGPS using ETD (RGPS-ETD) in phantom studies employing a cylinder phantom filled with technetium-99m solution attached to an instrument providing a simple harmonic motion. In the patient study, RGPS-DS was applied to data collected from 3 patients during a routine study of Tc-MAA pulmonary perfusion SPECT.

Results

In the phantom study, the calculation of COA indicated a good agreement between RGPS-DS and RGPS-ETD. With an oscillatory phantom movement amplitude of 30 mm, the amplitudes determined by RGPS-DS and RGPS-ETD (28.36 and 27.58 mm, respectively) were identical on considering a pixel size of 4.66 mm for reconstructed SPECT images. In the patient study, applicability of our method to patient data was demonstrated.

Conclusions

We have showed the feasibility of our method to obtain RGPS without ETD, and conclude that RGPS-DS may be an innovative and efficient technique in respiratory gated pulmonary perfusion SPECT. Further studies with a larger number of patients should demonstrate the accuracy of our method.

Keywords

Respiration tracking device SPECT Lung Dynamic acquisition 

Notes

Acknowledgments

The authors thank Prof. Tetsuo Ito, Prof. Nobuyuki Sugiura, Dr. Norio Tsuchiya, and Dr. Yoshihiro Komeya for scientific advice, and Hideo Morimoto, Hiroshi Takada, Ryou Inoue, Yuko Shintani, Shuhei Yoshida, and Toshiaki Kurokawa for assistance in data acquisition.

Conflict of interest

The authors declare that they have no conflict of interest and source of funding.

Supplementary material

Supplementary material 1 (MPG 1845 kb)

Supplementary material 2 (MPG 2528 kb)

Supplementary material 3 (MPG 1845 kb)

Supplementary material 4 (MPG 1933 kb)

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Copyright information

© The Japanese Society of Nuclear Medicine 2012

Authors and Affiliations

  • Kenta Sakaguchi
    • 1
  • Makoto Hosono
    • 1
  • Masakazu Otsuka
    • 2
  • Kohei Hanaoka
    • 2
  • Kimio Usami
    • 1
  • Tatsuro Uto
    • 2
  • Kazunari Ishii
    • 2
  1. 1.Division of Positron Emission Tomography, Institute of Advanced Clinical MedicineKinki University School of MedicineOsaka-SayamaJapan
  2. 2.Department of RadiologyKinki University School of MedicineOsaka-SayamaJapan

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