Annals of Nuclear Medicine

, Volume 26, Issue 7, pp 594–598

F-18 FDG uptake in borderline intraductal papillary neoplasms of the bile duct

Case report


Intraductal papillary neoplasm of the bile duct (IPN-B) has been recently proposed as the biliary counterpart of intraductal papillary mucinous neoplasm of the pancreas. Histologically, IPN-B can be classified into adenoma, borderline, carcinoma in situ, and invasive carcinoma. Two patients with suspected intraductal tumor underwent fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography. One patient showed an FDG-avid tumor in the right liver with SUVmax of 9.4 in early images and 11.3 in delayed images. The patient underwent complete tumor resection. Adenoma with high-grade dysplasia was confirmed by pathology. The other patient showed an FDG-avid polypoid lesion at the distal common bile duct with SUVmax of 5.4. The lesion was endoscopically resected. Histopathologic findings showed adenoma with low-grade dysplasia. These two cases highlight that IPN-B should be included in the differential diagnosis of abnormal biliary intraductal FDG accumulation along with carcinoma, and inflammatory and infectious processes.


Intraductal papillary neoplasm of the bile duct Bile duct F-18 FDG PET/CT 

Copyright information

© The Japanese Society of Nuclear Medicine 2012

Authors and Affiliations

  • Aisheng Dong
    • 1
  • Hui Dong
    • 2
  • Ling Zhang
    • 3
  • Changjing Zuo
    • 1
  1. 1.Department of Nuclear Medicine, Changhai HospitalSecond Military Medical UniversityShanghaiChina
  2. 2.Department of Pathology, Eastern Hepatobiliary Surgery HospitalSecond Military Medical UniversityShanghaiChina
  3. 3.Department of Gastroenterology, Changhai HospitalSecond Military Medical UniversityShanghaiChina

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