Annals of Nuclear Medicine

, Volume 26, Issue 7, pp 594–598

F-18 FDG uptake in borderline intraductal papillary neoplasms of the bile duct

Case report

Abstract

Intraductal papillary neoplasm of the bile duct (IPN-B) has been recently proposed as the biliary counterpart of intraductal papillary mucinous neoplasm of the pancreas. Histologically, IPN-B can be classified into adenoma, borderline, carcinoma in situ, and invasive carcinoma. Two patients with suspected intraductal tumor underwent fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography. One patient showed an FDG-avid tumor in the right liver with SUVmax of 9.4 in early images and 11.3 in delayed images. The patient underwent complete tumor resection. Adenoma with high-grade dysplasia was confirmed by pathology. The other patient showed an FDG-avid polypoid lesion at the distal common bile duct with SUVmax of 5.4. The lesion was endoscopically resected. Histopathologic findings showed adenoma with low-grade dysplasia. These two cases highlight that IPN-B should be included in the differential diagnosis of abnormal biliary intraductal FDG accumulation along with carcinoma, and inflammatory and infectious processes.

Keywords

Intraductal papillary neoplasm of the bile duct Bile duct F-18 FDG PET/CT 

Copyright information

© The Japanese Society of Nuclear Medicine 2012

Authors and Affiliations

  • Aisheng Dong
    • 1
  • Hui Dong
    • 2
  • Ling Zhang
    • 3
  • Changjing Zuo
    • 1
  1. 1.Department of Nuclear Medicine, Changhai HospitalSecond Military Medical UniversityShanghaiChina
  2. 2.Department of Pathology, Eastern Hepatobiliary Surgery HospitalSecond Military Medical UniversityShanghaiChina
  3. 3.Department of Gastroenterology, Changhai HospitalSecond Military Medical UniversityShanghaiChina

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