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Generation of planar images from lung ventilation/perfusion SPECT

  • Dale L. Bailey
  • Geoffrey P. Schembri
  • Benjamin E. Harris
  • Elizabeth A. Bailey
  • Robert A. Cooper
  • Paul J. Roach
Technical Note

Abstract

Objective

To develop a method of producing lung ventilation and perfusion (V/Q) planar images using forward projection of reconstructed single-photon emission computed tomography (SPECT) images through approximate attenuation (µ) maps generated from the lung emission scans alone, as transmission-based µ maps may not be routinely available.

Methods

Synthetic µ maps are derived from 99mTc photopeak and “scatter” windows for the attenuation correction of the SPECT images. The attenuation-corrected SPECT images are forward projected at appropriate angles to give the equivalent of planar images. This method allows high-count planar images, as well as the SPECT images, to be produced from a single SPECT acquisition. In addition, isolated “single lung” views of lateral and medial projections without “shine-through” from the contra-lateral lung, which have not been available previously, can be formed.

Results

Comparison of reprojected images produced from CT-derived or synthetic µ maps displayed similar detail and radiopharmaceutical distribution. In a blinded comparison of “true” planar images with those from reprojecting the SPECT data using the synthetic µ maps, no difference in mismatched defect detection was found, and hence it was confirmed that the reprojected planar images could replace true planar images with no loss in planar diagnostic sensitivity.

Conclusions

The reprojected planar images provide high-count, high-quality images, which are comparable with conventional 2D images.

Keywords

SPECT (single photon emission computed tomography) Lung Pulmonary embolus Gamma camera 

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Copyright information

© The Japanese Society of Nuclear Medicine 2008

Authors and Affiliations

  • Dale L. Bailey
    • 1
    • 2
    • 3
  • Geoffrey P. Schembri
    • 2
    • 3
  • Benjamin E. Harris
    • 2
    • 4
    • 5
  • Elizabeth A. Bailey
    • 3
  • Robert A. Cooper
    • 3
  • Paul J. Roach
    • 2
    • 3
  1. 1.Schools of Physics and Medical Radiation ScienceUniversity of SydneySydneyAustralia
  2. 2.Faculty of Medicine, Northern Clinical SchoolUniversity of SydneySydneyAustralia
  3. 3.Department of Nuclear MedicineRoyal North Shore HospitalSt Leonards, SydneyAustralia
  4. 4.Department of Respiratory MedicineRoyal North Shore HospitalSydneyAustralia
  5. 5.The Woolcock Institute of Medical ResearchUniversity of SydneySydneyAustralia

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