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Annals of Nuclear Medicine

, Volume 21, Issue 9, pp 505–511 | Cite as

Creation and characterization of Japanese standards for myocardial perfusion SPECT: database from the Japanese Society of Nuclear Medicine Working Group

  • Kenichi NakajimaEmail author
  • Shinichiro Kumita
  • Yoshio Ishida
  • Mitsuru Momose
  • Jun Hashimoto
  • Koichi Morita
  • Junichi Taki
  • Shohei Yamashina
  • Hirotaka Maruno
  • Masami Ogawa
  • Masahiro Kubota
  • Munehiro Takahashi
  • Tetsuro Odagawa
  • Koichi Yokozuka
ORIGINAL ARTICLE

Abstract

Objective

Standards for myocardial single-photon emission computed tomography (SPECT) adapted for a Japanese population were not available. The purpose of this study was to create standard files approved by the Japanese Society of Nuclear Medicine and to make known the characteristics of the myocardial perfusion pattern of this population.

Methods

With the collaboration of nine hospitals, a total of 326 sets of exercise–rest myocardial perfusion images were accumulated from subjects with a low likelihood of cardiac diseases. The normal database included a 99mTc-MIBI/tetrofosmin myocardial perfusion study with 360° (n = 80) and 180° (n = 56) rotations, 201Tl study with 360° (n = 115) and 180° rotations (n = 54) and a dual-isotope study with 360° rotation (n = 27). The projection images were transferred by digital imaging and communications in medicine (DICOM) format and reconstructed and analyzed with polar maps.

Results

The projection data from multiple centers were successfully transferred to a common format for SPECT reconstruction. When the average values were analyzed using a 17-segment model, myocardial counts in the septal segment differed significantly between 180° and 360° rotation acquisitions. Regional differences were observed between men and women in the inferior and anterior regions. A tracer difference between 99mTc and 201Tl was also observed in some segments. The attenuation patterns differed significantly between subjects from the United States and those from Japan.

Conclusions

Myocardial perfusion data that were specific for the Japanese population were generated. The normal database can serve a standard for nuclear cardiology work conducted in Japan.

Key words

Myocardial perfusion imaging SPECT Standard Japanese population Working Group of the Japanese Society of Nuclear Medicine 

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Copyright information

© The Japanese Society of Nuclear Medicine 2007

Authors and Affiliations

  • Kenichi Nakajima
    • 1
    Email author
  • Shinichiro Kumita
    • 1
  • Yoshio Ishida
    • 1
  • Mitsuru Momose
    • 1
  • Jun Hashimoto
    • 1
  • Koichi Morita
    • 1
  • Junichi Taki
    • 1
  • Shohei Yamashina
    • 1
  • Hirotaka Maruno
    • 1
  • Masami Ogawa
    • 1
  • Masahiro Kubota
    • 1
  • Munehiro Takahashi
    • 1
  • Tetsuro Odagawa
    • 1
  • Koichi Yokozuka
    • 1
  1. 1.Kanazawa University HospitalKanazawaJapan

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