Advertisement

Demographic and Clinical Characteristics of 5294 Jaw Cysts: A Retrospective Study of 38 Years

  • Paris TamiolakisEmail author
  • Grigorios Thermos
  • Konstantinos I. Tosios
  • Alexandra Sklavounou-Andrikopoulou
Original Paper

Abstract

The aim of the present study is to report the demographic and clinical characteristics of all jaw cysts diagnosed in a single Oral Pathology Department. 5294 cases of jaw cysts diagnosed during a 38-year period were retrospectively collected and classified according to the latest classification of Head and Neck Tumors of the World Health Organization. The patients’ gender and age, as well as the main clinical features of the cysts were retrieved from biopsy report forms. Jaw cysts were more common in male patients, with a male to female ratio of 1.6:1. Most patients were in the 4th–6th decade of life, with a mean age of 42.3 ± 16.1 years. There was no jaw predilection and the majority of lesions were more commonly encountered in the anterior region of the maxilla, followed by the molar region of the mandible. The most common jaw cyst was radicular cyst followed by dentigerous cyst, residual cyst and odontogenic keratocyst. The majority of jaw cysts are of inflammatory origin and represent a sequale of pulp necrosis. However, other type of jaw cysts may also be found.

Keywords

Jaw cysts Odontogenic cysts Jaw cysts epidemiology 

Notes

Compliance with Ethical Standards

Conflict of interest

All authors declare that the have no conflict of interest.

References

  1. 1.
    Johnson NR, Savage NW, Kazoullis S, Batstone MD. A prospective epidemiological study for odontogenic and non-odontogenic lesions of the maxilla and mandible in Queensland. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115:515–22.CrossRefGoogle Scholar
  2. 2.
    Jones AV, Franklin CD. An analysis of oral and maxillofacial pathology found in adults over a 30-year period. J Oral Pathol Med. 2006;35:392–401.CrossRefGoogle Scholar
  3. 3.
    Shear M, Speight P. Cysts of the Oral and Maxillofacial Regions. Ames: Wiley-Blackwell; 2007. Ch1; pp. 1–2.CrossRefGoogle Scholar
  4. 4.
    El-Naggar AK, Chan JKC, Grandis JR, Takata T, Sootweg P. World Health Organization classification of head and neck tumours. 4th ed. Lyon: IARC; 2017, p. 232–40.Google Scholar
  5. 5.
    Barnes L, Eveson JW, Reichart P, Sidransky D, eds. WHO classification of tumors. Pathology and genetics of head and neck tumours. Lyon: IARC Press, 2005, pp. 284–327.Google Scholar
  6. 6.
    Pindborg J, Kramer I. WHO international histological classification of tumours. Histological typing of odontogenic tumours, jaw cysts and allied lesions. Geneva: WHO; 1971.Google Scholar
  7. 7.
    Kramer I, Pindborg J, Shear M. WHO international histological classification of tumours. Histological typing of odontogenic tumours. 2nd ed. Berlin: Springer-Verlag; 1992.CrossRefGoogle Scholar
  8. 8.
    Martin LHC, Speight PM. Odontogenic cysts: an update. Diagn Histopathol. 2017;23:260–5.CrossRefGoogle Scholar
  9. 9.
    da Silva LP, Gonzaga AK, Severo ML, et al. Epidemiologic study of odontogenic and non-odontogenic cysts in children and adolescents of a Brazilian population. Med Oral Patol Oral Cir Bucal. 2018;23:e49–53.Google Scholar
  10. 10.
    Lo Muzio L, Mascitti M, Santarelli A, et al. Cystic lesions of the jaws: a retrospective clinicopathologic study of 2030 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017;124:128–38.CrossRefGoogle Scholar
  11. 11.
    Jaeger F, de Noronha MS, Silva ML, et al. Prevalence profile of odontogenic cysts and tumors on Brazilian sample after the reclassification of odontogenic keratocyst. J Craniomaxillofac Surg. 2017;45:267–70.CrossRefGoogle Scholar
  12. 12.
    Khosravi N, Razavi SM, Kowkabi M, Navabi AA. Demographic distribution of odontogenic cysts in Isfahan (Iran) over a 23-year period (1988–2010). Dent Res J (Isfahan). 2013;10:162–7.CrossRefGoogle Scholar
  13. 13.
    Tekkesin MS, Olgac V, Aksakalli N, Alatli C. Odontogenic and nonodontogenic cysts in Istanbul: analysis of 5088 cases. Head Neck. 2012;34:852–5.CrossRefGoogle Scholar
  14. 14.
    Sharifian MJ, Khalili M. Odontogenic cysts: a retrospective study of 1227 cases in an Iranian population from 1987 to 2007. J Oral Sci. 2011;53:361–7.CrossRefGoogle Scholar
  15. 15.
    Grossmann SM, Machado VC, Xavier GM, et al. Demographic profile of odontogenic and selected nonodontogenic cysts in a Brazilian population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104:e35–41.CrossRefGoogle Scholar
  16. 16.
    Ochsenius G, Escobar E, Godoy L, Peñafiel C. Odontogenic cysts: analysis of 2944 cases in Chile. Med Oral Patol Oral Cir Bucal. 2007;12:E85–91.Google Scholar
  17. 17.
    Daley TD, Wysocki GP, Pringle GA. Relative incidence of odontogenic tumors and oral and jaw cysts in a Canadian population. Oral Surg Oral Med Oral Pathol. 1994;77:276–80.CrossRefGoogle Scholar
  18. 18.
    Chrcanovic BR, Gomez RS. Gingival cyst of the adult, lateral periodontal cyst, and botryoid odontogenic cyst: an updated systematic review. Oral Dis. 2017.  https://doi.org/10.1111/odi.12808.Google Scholar
  19. 19.
    Chrcanovic BR, Gomez RS. Glandular odontogenic cyst: an updated analysis of 169 cases reported in the literature. Oral Dis. 2018;24:717–24.CrossRefGoogle Scholar
  20. 20.
    MacDonald-Jankowski DS. Keratocystic odontogenic tumour: systematic review. Dentomaxillofac Radiol. 2011;40:1–23.CrossRefGoogle Scholar
  21. 21.
    Bree AF, Shah MR, BCNS Colloquium Group. Consensus statement from the first international colloquium on basal cell nevus syndrome (BCNS). Am J Med Genet A. 2011;155A:2091–7.CrossRefGoogle Scholar
  22. 22.
    Pastorino L, Pollio A, Pellacani G, et al. Novel PTCH1 mutations in patients with keratocystic odontogenic tumors screened for nevoid basal cell carcinoma (NBCC) syndrome. PLoS ONE. 2012;7:e43827.CrossRefGoogle Scholar
  23. 23.
    Al-Moraissi EA, Dahan AA, Alwadeai MS, et al. What surgical treatment has the lowest recurrence rate following the management of keratocystic odontogenic tumor?: a large systematic review and meta-analysis. J Craniomaxillofac Surg. 2017;45:131–44.CrossRefGoogle Scholar
  24. 24.
    Macdonald-Jankowski DS. Orthokeratinized odontogenic cyst: a systematic review. Dentomaxillofac Radiol. 2010;39:455–67.CrossRefGoogle Scholar
  25. 25.
    de Arruda JAA, Monteiro JLGC, Abreu LG, et al. Calcifying odontogenic cyst, dentinogenic ghost cell tumor, and ghost cell odontogenic carcinoma: a systematic review. J Oral Pathol Med. 2018.  https://doi.org/10.1111/jop.12727.Google Scholar
  26. 26.
    Barros CCDS, Santos HBP, Cavalcante IL, et al. Clinical and histopathological features of nasopalatine duct cyst: a 47-year retrospective study and review of current concepts. J Craniomaxillofac Surg. 2018;46:264–8.CrossRefGoogle Scholar
  27. 27.
    Vasconcelos R, de Aguiar MF, Castro W, de Araújo VC, Mesquita R. Retrospective analysis of 31 cases of nasopalatine duct cyst. Oral Dis. 1999;5:325–8.CrossRefGoogle Scholar
  28. 28.
    Tsuneki M, Maruyama S, Yamazaki M, et al. Inflammatory histopathogenesis of nasopalatine duct cyst: a clinicopathological study of 41 cases. Oral Dis. 2013;19:415–24.CrossRefGoogle Scholar
  29. 29.
    Motamedi MH, Behroozian A, Azizi T, et al. Assessment of 120 maxillofacial aneurysmal bone cysts: a nationwide quest to understand this enigma. J Oral Maxillofac Surg. 2014;72:1523–30.CrossRefGoogle Scholar
  30. 30.
    Perdigão PF, Silva EC, Sakurai E, et al. Idiopathic bone cavity: a clinical, radiographic, and histological study. Br J Oral Maxillofac Surg. 2003;41:407–9.CrossRefGoogle Scholar
  31. 31.
    Chadwick JW, Alsufyani NA, Lam EW. Clinical and radiographic features of solitary and cemento-osseous dysplasia-associated simple bone cysts. Dentomaxillofac Radiol. 2011;40:230–5.CrossRefGoogle Scholar
  32. 32.
    Peacock ME, Krishna R, Gustin JW, et al. Retrospective study on idiopathic bone cavity and its association with cementoosseous dysplasia. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;119:e246-51.CrossRefGoogle Scholar
  33. 33.
    Philipsen HP, Reichart PA, Ogawa I, Suei Y, Takata T. The inflammatory paradental cyst: a critical review of 342 cases from a literature survey, including 17 new cases from the author’s files. J Oral Pathol Med. 2004;33:147–55.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Oral Medicine and Pathology, Department of Dentistry, School of Health SciencesNational and Kapodistrian University of AthensAthensGreece
  2. 2.Oral MedicineDublin Dental University HospitalDublinIreland

Personalised recommendations