Tongue Lumps and Bumps: Histopathological Dilemmas and Clues for Diagnosis
Exophytic lesions of the tongue encompass a diverse spectrum of entities. These are most commonly reactive, arising in response to local trauma but can also be neoplastic of epithelial, mesenchymal or miscellaneous origin. In most cases, the microscopic examination is likely to provide a straightforward diagnosis. However, some cases can still raise microscopic diagnostic dilemmas, such as conditions that mimic malignancies, benign tumors with overlapping features and anecdotal lesions. A series of “lumps and bumps” of the tongue are presented together with suggested clues that can assist in reaching a correct diagnosis, emphasizing the importance of the clinico-pathological correlations.
KeywordsTongue Lumps and bumps Pseudoepitheliomatous hyperplasia Verrucous lesions Neural lesion Spindle cell tumors Adipocytic tumors Lymphoid-rich lesions
No funding was received for this study.
Compliance with Ethical Standards
Conflict of interest
Irit Allon, Marilena Vered declares, Ilana Kaplan declares that they have no conflict of interest.
Research Involving Human Participants and/or Animals
This article does not contain any studies with human participants performed by any of the authors.
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