Sclerosing Microcystic Adenocarcinoma: Report of a Rare Case and Review of Literature

  • Ranran Zhang
  • Alain Cagaanan
  • Gholam-Reza Hafez
  • Rong Hu
Original Paper


Sclerosing microcystic adenocarcinoma is an exceedingly rare entity occurring in the mucosal surfaces of the head and neck that closely resembles cutaneous microcystic adnexal carcinoma. Here, we report a case of sclerosing microcystic adenocarcinoma that presented as a vague mass at the floor of the mouth in a 55-year-old woman. The pathology features and the diagnostic challenges, especially in the biopsy and margin evaluation are discussed here. Similar cases published in the English literatures are reviewed.


Sclerosing microcystic adenocarcinoma Microcystic adnexal carcinoma Head and neck Mucosa 



We would like to thank Dr. Ricardo Lloyd and Dr. Aaron Wieland for their input in this case.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Ranran Zhang
    • 1
  • Alain Cagaanan
    • 1
  • Gholam-Reza Hafez
    • 1
  • Rong Hu
    • 1
  1. 1.Department of Pathology and Laboratory MedicineUniversity of Wisconsin School of Medicine and Public HealthMadisonUSA

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