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Head and Neck Pathology

, Volume 13, Issue 4, pp 692–698 | Cite as

Laryngeal Basaloid Squamous Cell Carcinoma with a Substantial Spindle Cell Component: Case Presentation and Updated Review of Literature

  • Deepak Pandiar
  • Sangeetha K. NayanarEmail author
  • Basavaraj Ankalkoti
  • Sajith Babu
Case Report
  • 108 Downloads

Abstract

Basaloid squamous cell carcinoma with spindle cell component is an uncommon aggressive variety of squamous cell carcinoma with only a few reported cases in literature. Histologically a combination of basaloid squamous cell carcinoma and spindle cell squamous cell carcinoma is appreciated and immunohistochemistry serves a role in differentiation from malignant neoplasms of salivary gland or neuro-endocrine origin. Prime treatment modality is combination of surgery and external beam radiotherapy. A case of basaloid squamous cell carcinoma with proliferation of bizarre mesenchymal component is being reported here with an updated literature review.

Keywords

Basaloid Epithelial mesenchymal transition Glottis Spindle cell 

Notes

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Statement

The manuscript is based on the total laryngectomy specimen received in our department with no additional psychological, physical and financial burden for the patient.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Deepak Pandiar
    • 1
  • Sangeetha K. Nayanar
    • 1
    Email author
  • Basavaraj Ankalkoti
    • 2
  • Sajith Babu
    • 2
  1. 1.Department of Clinical Laboratory Services and Translational ResearchMalabar Cancer CenterThalasseryIndia
  2. 2.Department of Surgical OncologyMalabar Cancer CenterThalasseryIndia

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