Advertisement

Head and Neck Pathology

, Volume 11, Issue 4, pp 580–583 | Cite as

Hyalinizing Clear Cell Carcinoma of the Tonsil: A Case Report

  • Bridget Burgess
  • Vijayalakshmi Ananthanarayanan
  • Steven Charous
Case Report

Abstract

Hyalinzing clear cell carcinoma is a rare tumor of the oral cavity and is even more rarely located in the tonsil. Here, we present a case report of a pedunculated tonsillar mass in a nearly asymptomatic patient that was present for 2 years prior to removal. Complete surgical excision was achieved and no adjuvant therapy was recommended. We include a discussion of this rare pathology and its typical clinical presentation and course.

Keywords

Hyalinizing clear cell carcinoma Tonsil cancer Salivary gland cancer 

Notes

Compliance with Ethical Standards

Conflict of interest

There is no conflicts of interest for this case report.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

References

  1. 1.
    Milchgrub S, Gnepp DR, Vuitch F, et al. Hyalinizing clear cell carcinoma of the salivary gland. Am J Surg Pathol. 1994;18(1):74–82.CrossRefPubMedGoogle Scholar
  2. 2.
    Barnes L, Eveson JW, Reichart P, et al. Clear cell carcinoma not otherwise specified. World health organization classification of tumours. Pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005. pp. 227–8.Google Scholar
  3. 3.
    Antonescu CR, Katabi N, Zhang L, et al. EWSR1-ATF1 fusion is a novel and consistent finding in hyalinizing clear cell carcinoma of salivary gland. Genes Chromosomes Cancer. 2011;50(7):559–70.CrossRefPubMedGoogle Scholar
  4. 4.
    Nakano T, Yamamoto H, Nishijima T, et al. Hyalinizing clear cell carcinoma with EWSR1-ATF1 fusion gene: report of three cases with molecular analyses. Virchows Arch. 2015;466(1):37–43.CrossRefPubMedGoogle Scholar
  5. 5.
    Kauzman A, Tabet JC, Stiharu TI. Hyalinizing clear cell carcinoma: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(1):e26–34.CrossRefPubMedGoogle Scholar
  6. 6.
    O’Sullivan-Mejia ED, Massey HD, Faquin WC, et al. Hyalinizing clear cell carcinoma: report of eight cases and a review of literature. Head Neck Pathol. 2009;3(3):179–85.CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7.
    Solar AA, Schmidt BL, Jordan RC, et al. Hyalinizing clear cell carcinoma: case series and comprehensive review of the literature. Cancer. 2009;115(1):75–83.CrossRefPubMedGoogle Scholar
  8. 8.
    Su HK, Wang BY, Mannan AA, et al. Very delayed cervical lymph node metastases from hyalinizing clear cell carcinoma: report of 2 cases. Head Neck. 2015;37(2):E19–21.CrossRefPubMedGoogle Scholar
  9. 9.
    Albergotti WG, Bilodeau EA, Byrd JK, et al. Hyalinizing clear cell carcinoma of the head and neck: case series and update. Head Neck. 2016;38(3):426–33.CrossRefPubMedGoogle Scholar
  10. 10.
    Hijjawi SB, Abdullah SE, Abdelhadi K, et al. Hyalinizing clear cell carcinoma of the tonsil and its treatment. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114(2):e32–6.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Loyola University Medical CenterMaywoodUSA

Personalised recommendations