Head and Neck Pathology

, Volume 7, Issue 1, pp 35–39

Unmasking MASC: Bringing to Light the Unique Morphologic, Immunohistochemical and Genetic Features of the Newly Recognized Mammary Analogue Secretory Carcinoma of Salivary Glands

North American Society of Head and Neck Pathology Companion Meeting, March 3, 2013, Baltimore, Maryland

DOI: 10.1007/s12105-013-0429-0

Cite this article as:
Bishop, J.A. Head and Neck Pathol (2013) 7: 35. doi:10.1007/s12105-013-0429-0


Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland neoplasm that is characterized by its striking morphologic and molecular similarities to secretory carcinoma of the breast. This review highlights the characteristic clinical, histologic, immunophenotypic, and molecular features of MASC, and draws attention to the differential diagnosis of this increasingly recognized tumor.


Mammary analogue secretory carcinoma Secretory carcinoma Acinic cell carcinoma ETV6–NTRK3 Mammaglobin 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of PathologyThe Johns Hopkins University School of MedicineBaltimoreUSA

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