Head and Neck Pathology

, Volume 5, Issue 1, pp 31–35

A Review of NUT Midline Carcinoma

Proceedings of the NASHNP Companion Meeting, February, 2011, San Antonio, TX


Nut midline carcinomas are uncommon carcinomas characterized by chromosomal rearrangements that involve the gene encoding the nuclear protein of the testis (NUT). This article reviews the clinicopathologic features of these malignancies. Ancillary testing is discussed as well as the pathologic differential diagnosis.


Nut midline carcinoma t(15;19) Immunohistochemistry Fluorescent in situ hybridization 


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Dept of PathologyUVA Health System, University of VirginiaCharlottesvilleUSA

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