Chemical shift assignments of retinal guanylyl cyclase activating protein 5 (GCAP5)
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Retinal membrane guanylyl cyclase (RetGC) in photoreceptor rod and cone cells is regulated by a family of guanylyl cyclase activating proteins (GCAP1-7). GCAP5 is expressed in zebrafish photoreceptors and promotes Ca2+-dependent regulation of RetGC enzymatic activity that regulates visual phototransduction. We report NMR chemical shift assignments of the Ca2+-free activator form of GCAP5 (BMRB No. 27705).
KeywordsRetinal guanylyl cyclase RetGC GCAP5 EF-hand Phototransduction
We thank Jeff Walton for technical support and help with NMR experiments. Work supported by NIH Grant No. (EY012347) to J.B.A.
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